| 100% | ONEARM | 6 | Feature of the villain in "The Fugitive" |
| 81% | ONEARM | 6 | Characteristic of the villain in "The Fugitive" |
| 65% | GHOSTFACE | 9 | Nickname of the villain in the Scream movies |
| 65% | LUNARMOUTH | 10 | Facial feature of the Man in the Moon? |
| 64% | VIEW | 4 | Feature of a house in the hills |
| 64% | AGEGAP | 6 | Feature of the marriage in May December |
| 63% | CRATER | 6 | Any facial feature of the man in the moon, in reality |
| 62% | SERIF | 5 | Feature of a letter in the Times Roman typeface |
| 62% | ACCENT | 6 | Feature of the "e" in 57-Across |
| 62% | EAR | 3 | Feature of “The Powerpuff Girls” villain HIM that ends in a point |
| 62% | GOATEE | 6 | Feature of “The Powerpuff Girls” villain HIM that ends in a point |
| 61% | IAGO | 4 | One of the villains in 'Othello' by Shakespeare |
| 61% | HAMAN | 5 | Villain in the book of Esther |
| 61% | LORRE | 5 | Player of the villain in "The Man Who Knew Too Much" |
| 60% | HAMAN | 5 | Villain in the Jewish holiday of Purim |
| 60% | CAPS | 4 | Feature of the last word in this CLUE |
| 60% | DOME | 4 | Feature of the Capitol building in Washington, DC |
| 59% | DRNO | 4 | Villain in the title of a James Bond book |
| 59% | STEM | 4 | Feature of the items in the first parts of 21- and 49-Across and 3- and 29-Down |
| 58% | PLEAT | 5 | One feature of the outfits that the Clanadonians wear in their gigs |
| 58% | STEPS | 5 | Feature of the Philadelphia Art Museum made famous in "Rocky" |
| 58% | SCAR | 4 | Facial feature of the Bond villain Ernst Blofeld |
| 58% | DUNE | 4 | Sandy feature of the National Park in Indiana |
| 58% | HOTNESSK | 8 | Feature of summers in the Sahara |
| 57% | NOSE | 4 | Feature in the middle of the face |
| 57% | POLESAPART | 10 | In complete opposition ... and a feature of the four other longest answers |
| 57% | CLUBBER | 7 | First name of Mr. Lang, the villain in Rocky III |
| 56% | IAGO | 4 | Villain hiding out in the east of Santiago |
| 56% | HOLE | 4 | Feature in the middle of a 6-Across |
| 56% | TSTRAP | 6 | Feature of high heels popularized in the 1920s |