| 100% | CIA | 3 | Federal espionage group: Abbr. |
| 94% | CIA | 3 | Secretive, federal espionage group: Abbr. |
| 70% | CIA | 3 | Federal espionage organization: Abbr. |
| 70% | CIA | 3 | US espionage group: Abbr. |
| 70% | CIA | 3 | American espionage group: Abbr. |
| 68% | EPA | 3 | Federal antipollution group: Abbr. |
| 68% | DEA | 3 | Federal antinarcotics group: Abbr. |
| 68% | GAO | 3 | Federal auditing group: Abbr. |
| 67% | CIA | 3 | Espionage group in "Homeland": Abbr. |
| 66% | CIA | 3 | Espionage group headquartered in Virginia: Abbr. |
| 62% | CIA | 3 | Covert federal group: Abbr. |
| 61% | FDA | 3 | Federal group that oversees medications: Abbr. |
| 61% | EPA | 3 | Federal group that monitors pollution: Abbr. |
| 61% | NEA | 3 | Federal group that funds museums: Abbr. |
| 61% | IRS | 3 | Federal group that conducts audits: Abbr. |
| 60% | CIA | 3 | US espionage group featured in the Bourne movies: Abbr. |
| 60% | USDA | 4 | Federal group that approves meat products: Abbr. |
| 60% | DEA | 3 | Federal group that goes after narcotics: Abbr. |
| 60% | USDA | 4 | Federal group stamps meat and poultry: Abbr. |
| 60% | EPA | 3 | Federal group that supports renewable energy: Abbr. |
| 60% | DEA | 3 | Federal group that tracks meth labs: Abbr. |
| 60% | EPA | 3 | Federal group that monitors water pollution: Abbr. |
| 60% | EPA | 3 | Federal group that monitors air quality: Abbr. |
| 60% | EPA | 3 | Federal group involved in water monitoring: Abbr. |
| 60% | DEA | 3 | Federal crime-busting group in "Narcos": Abbr. |
| 60% | EPA | 3 | Federal group concerned with oil spills: Abbr. |
| 60% | DEA | 3 | Federal group that goes after traffickers: Abbr. |
| 60% | SEC | 3 | Federal group that charged 17-Across: Abbr. |
| 60% | NSA | 3 | Federal group nicknamed "the Puzzle Palace": Abbr. |
| 60% | IRS | 3 | Federal group that issues tax refunds: Abbr. |