| 100% | BEDROCK | 7 | Fictional prehistoric town that is the setting for "The Flintstones" |
| 70% | ARLEN | 5 | Fictional town in Texas that is the setting for "King of the Hill" |
| 63% | YORK | 4 | New New ___, fictional futuristic city that is the setting for "Futurama" |
| 54% | TROY | 4 | Ancient Greek city that was the setting for the Trojan War |
| 53% | KYOTO | 5 | Former Japanese capital that was the setting for the ___ Protocol, a 1997 agreement |
| 52% | INN | 3 | Type of establishment that was the setting for "Newhart" |
| 51% | PALAU | 5 | Micronesian island that was the setting for a season of "Survivor" |
| 51% | MIT | 3 | Science-focused school that was the setting for "Good Will Hunting": Abbr. |
| 51% | FIJI | 4 | South Pacific island nation that was the setting for "Survivor" season 14 |
| 50% | QUAHOG | 6 | Fictional Rhode Island city that's the setting for 15-Across |
| 50% | NESTEGGS | 8 | Funds that are set aside for the future: 2 wds. |
| 49% | GONDOR | 6 | Middle-earth kingdom that is the setting for "The Lord of the Rings: The Return of the King" |
| 48% | LAKE | 4 | ___ Wallenpaupack, water body in Scranton that was the setting for a Dunder Mifflin cruise party in "The Office" |
| 48% | ISLANUBLAR | 10 | The fictional Central American island in Costa Rica which is the setting for 26a: 2 wds. |
| 48% | MITHRIL | 7 | Fictional metal that was the material for Frodo's shirt of mail that saves his life |
| 47% | WONDERLAND | 10 | Fantasy world that is the setting for Alice's adventures, and also for 34a, 45a, 5d, 33d, and 39d |
| 47% | DEVON | 5 | English county that's the setting for Agatha Christie's "And Then There Were None" |
| 46% | TWIN | 4 | "___ Peaks," mystery series named after the fictional Washington town it is set in |
| 46% | ARLEN | 5 | Fictional Texas town in which "King of the Hill" is set |
| 45% | KONG | 4 | "King ___," 2005 film that is set on the fictional Skull Island |
| 44% | FALLS | 5 | "Gravity ___," animated mystery show named after the fictional town it is set in |
| 43% | TROY | 4 | Ancient city that is the setting of the "Iliad" |
| 43% | VIETNAM | 7 | War that's the setting for the film Apocalypse Now |
| 43% | RAM | 3 | Animal that is the symbol for the zodiac sign Aries |
| 43% | CRAB | 4 | Crustacean that is the symbol for the zodiac sign Cancer |
| 43% | OTRANTO | 7 | Town on the SE tip of Italy that's the title setting for a Horace Walpole novel |
| 42% | OAHU | 4 | Hawaiian island that is home to Honolulu and was the setting for "50 First Dates" |
| 42% | ABSCAM | 6 | Sting that was the inspiration for the 2013 film "American Hustle" |
| 42% | BEAN | 4 | Seed that is the source for 20a |
| 42% | IAMACAMERA | 10 | Play that was the basis for "Cabaret" |