| 100% | HARDYBOYS | 9 | Fictional young male detectives who first appeared in a 1927 book credited to the pen name Franklin W Dixon: 2 wds. |
| 72% | NANCYDREW | 9 | Fictional young female detective who first appeared in a 1930 book credited to the pen name Carolyn Keene: 2 wds. |
| 67% | BOBBSEYTWINS | 12 | Fictional young brother-and-sister detectives who first appeared in a 1904 book credited to the pen name Laura Lee Hope: 2 wds. |
| 48% | TRIXIEBELDEN | 12 | Fictional young female detective who first appeared in a 1948 book by Julie Campbell Tatham: 2 wds. |
| 31% | WONDERWOMAN | 11 | Fictional superhero appearing in comic books who is a founding member of the Justice League and an ambassador of the Amazon people: 2 wds. |
| 29% | SEXTONBLAKE | 11 | Fictional detective who first appeared in 1893 story The Missing Millionaire by Hal Meredeth aka Harry Blyth |
| 28% | DOCTORSTRANGE | 13 | Fictional superhero appearing in comic books who is the primary protector of Earth against magical and mystical threats: 2 wds. |
| 28% | NANCYDREW | 9 | Fictional girl detective who first appeared in 1930 novel The Secret of the Old Clock by Carolyn Keene |
| 28% | KENDALLJENNER | 13 | World's highest-paid model as of 2017, who first appeared in a reality TV show with her famous half-sisters: 2 wds. |
| 26% | CHAN | 4 | Fictional character who first appeared in "The House Without a Key" |
| 26% | CAMJANSEN | 9 | Young female detective in books written by David A. Adler since 1980: 2 wds. |
| 26% | THEEXCHANGE | 11 | 2023 novel by 41-Across that features lawyer Mitch McDeere, who first appeared in the 1991 novel "The Firm" (2 wds.) |
| 25% | HUCKLEBERRY | 11 | ___ Finn, a fictional character who first appeared in 51a and is a friend of the protagonist |
| 25% | GEORGESMILEY | 12 | Fictional spy who first appeared in "Call for the Dead" |
| 25% | NANCYDREW | 9 | Young female detective in books written under the pseudonym Carolyn Keene since 1930: 2 wds. |
| 24% | MARKTWAIN | 9 | Pen name of Samuel Clemens who is famous for his book "The Adventures of Tom Sawyer": 2 wds. |
| 24% | SHOHEIOHTANI | 12 | Japanese MLB player who was the first player in history to be a pitcher and hitter in the All-Star Game, in 2021: 2 wds. |
| 24% | KENDALLJENNER | 13 | Model who appeared in a Pepsi commercial which had to be later removed due to a lot of backlash in 2017: 2 wds. |
| 24% | CHAN | 4 | Charlie —, detective creation of Earl Biggers who first appeared in The House Without a Key |
| 24% | PONCEDELEON | 11 | Explorer who in 1513 became the first European to set foot in 14-Across, and gave the state its name: 3 wds. |
| 24% | CHAN | 4 | Charlie —, detective creation of Earl Biggers who first appeared in 1925 novel The House Without a Key |
| 23% | JIMMYCARTER | 11 | President who comedically appeared in a 1994 episode of "Home Improvement": 2 wds. |
| 23% | LISALESLIE | 10 | Basketball Hall of Fame inductee who was the first player to dunk in a WNBA game: 2 wds. |
| 23% | THOR | 4 | Superhero with a hammer who appeared in the first issue of the comic book "The Avengers" |
| 23% | BARTSIMPSON | 11 | Bratty toon whose balloon first appeared in the 1990 Macy's Thanksgiving Day Parade: 2 wds. |
| 23% | MICKEYMOUSE | 11 | Disney character whose balloon first appeared in the 1934 Macy's Thanksgiving Day Parade: 2 wds. |
| 23% | LEWISCARROLL | 12 | Pen name of Charles Dodgson, who wrote "Alice's Adventures in Wonderland": 2 wds. |
| 23% | BARACKOBAMA | 11 | President who comedically appeared in a 2007 episode of "Saturday Night Live": 2 wds. |
| 23% | KEVINHART | 9 | "Jumanji: Welcome to the Jungle" actor who stars in "Night School": 2 wds. |
| 23% | KATIESOWERS | 11 | First woman in the NFL to coach in a Super Bowl, for the San Francisco 49ers in 2020: 2 wds. |