| 100% | EXE | 3 | File extension for an application |
| 55% | JPG | 3 | File extension for a digital image |
| 54% | TIF | 3 | File extension for some hi-res images |
| 54% | PDF | 3 | File extension for text or graphics: Abbr. |
| 53% | PPT | 3 | Common file extension for a slideshow |
| 53% | XLS | 3 | Spreadsheet file extension for Microsoft Excel |
| 53% | BMP | 3 | Extension for bitmap files |
| 52% | PNG | 3 | Image file extension for lossless data compression |
| 52% | EXE | 3 | Palindromic file extension for a PC program |
| 52% | APK | 3 | Extension for Android software files |
| 52% | SYS | 3 | Extension for Windows driver files |
| 51% | SYST | 4 | Extension for some Windows driver files |
| 51% | XLS | 3 | File suffix for an Excel spreadsheet |
| 50% | EXE | 3 | Application file extension |
| 50% | JAR | 3 | File extension used for archiving Java class files |
| 49% | TXT | 3 | File extension that's an alternative to ".doc" |
| 49% | TXT | 3 | Extension for files with no images in them |
| 49% | BUYSOMETIME | 11 | Ask for an extension, for example |
| 48% | JPEG | 4 | Four-letter format for an image file |
| 48% | FLEAPOWDER | 10 | Application for an itchy pet |
| 47% | TXT | 3 | Extension on an unformatted document file |
| 47% | ASP | 3 | An acronym for application service provider |
| 46% | DYE | 3 | Application for hair or an Easter egg |
| 46% | INI | 3 | Extension used for Windows configuration files, once |
| 46% | EXE | 3 | Extension seen on installation files for programs |
| 45% | EXE | 3 | Application-launching file extension |
| 44% | SCR | 3 | File extension of an app that kicks in after the PC's been inactive |
| 41% | GOBELLYUP | 9 | File for Chapter 11 ... or do an 18-, 20-, 60- or 64-Across |
| 40% | GIF | 3 | Animated Internet file suffix that is also an anagram for 27d: Abbr. |
| 39% | TAB | 3 | File extension |