| 100% | ASTA | 4 | Film role played by Skippy |
| 75% | ASTA | 4 | Film terrier played by Skippy |
| 71% | CAMEO | 5 | Tiny film role played by a star |
| 71% | SATAN | 5 | Film role played by both Vincent Price and Bill Cosby |
| 68% | BOND | 4 | Role played by six different actors across 24 films |
| 65% | TONTO | 5 | Role played in films by Chief Thundercloud |
| 65% | ROMEO | 5 | Role played by Leonardo DiCaprio on film and Orlando Bloom on stage |
| 63% | EVITA | 5 | Musical role played by Madonna on film and Patti LuPone on Broadway |
| 54% | CRITIC | 6 | Role played by everyone, it's said |
| 54% | IRIS | 4 | Role played by both Kate and Judi |
| 54% | ASTA | 4 | Repeated film role for Skippy |
| 53% | RYAN | 4 | Role played by Baldwin, Ford, Affleck and Pine |
| 53% | LANCELOT | 8 | Role played by Richard Gere and John Cleese |
| 53% | NEO | 3 | Role played by Keanu Reeves in three movies |
| 52% | RICHARDKIMBLE | 13 | Role played by 18- and 44-Across: 2 wds. |
| 52% | LEO | 3 | Uncle ___ ("Seinfeld" role played by Len Lesser) |
| 52% | UNCLELEO | 8 | Lesser "Seinfeld" role played by Len Lesser |
| 52% | ROGUE | 5 | “X-Men” role played by Anna Paquin |
| 52% | EVE | 3 | TV title role played by Sandra Oh |
| 51% | NERO | 4 | Role played by 52-Across in "The Story of Mankind" |
| 51% | BOND | 4 | Role played by Connery, Lazenby, Moore, Dalton, Brosnan, and Craig |
| 51% | UNCLEJESSE | 10 | Role played by 18-Across on "Full House": 2 wds. |
| 51% | NED | 3 | Role played by Sean Bean in "Game of Thrones," fondly |
| 51% | PERSONA | 7 | Someone's character; role played by an actor |
| 51% | MARYTODDLINCOLN | 15 | Historical role played by Sally Field in 2012 |
| 51% | MONK | 4 | Former TV title role played by Tony Shalhoub |
| 51% | ASTA | 4 | Film role for the dog Skippy |
| 51% | DRNO | 4 | Film villain played by Joseph Wiseman |
| 51% | ULEE | 4 | Film beekeeper played by Peter Fonda |
| 50% | ATTILA | 6 | Historic role played by Jack Palance and Anthony Quinn |