| 100% | CULTURESHOCK | 12 | First-time visitor's distress, perhaps |
| 56% | WOBBLES | 7 | Wears heels for the first time, perhaps |
| 50% | CULTURE | 7 | ___ shock (unprepared tourist's distress, perhaps) |
| 50% | PAST | 4 | Time traveler's destination, perhaps |
| 50% | TEEN | 4 | First-time voter, perhaps |
| 47% | NEST | 4 | Bird's first home, perhaps |
| 47% | MAMA | 4 | Baby's first word, perhaps |
| 47% | TRALA | 5 | Singer's first syllables, perhaps |
| 47% | DADA | 4 | Baby's first word, perhaps |
| 47% | DRAFT | 5 | Essay's first copy, perhaps |
| 47% | MAMA | 4 | Child's first word, perhaps |
| 47% | MAMA | 4 | Baby's first words, perhaps |
| 46% | FAQ | 3 | Helpful web page for first-time visitors: Abbr. |
| 46% | OPENTHEBIDDING | 14 | Raise one’s hand first, perhaps |
| 46% | EENIE | 5 | Indecisive child's first word, perhaps |
| 46% | SIXAM | 5 | Schoolteacher's wake-up time, perhaps |
| 45% | GRAD | 4 | Prof's visitor, perhaps |
| 45% | ROOKIE | 6 | First timer |
| 45% | CENTRAL | 7 | Alphabetically first time zone in the contiguous U.S. |
| 45% | SEMI | 4 | Time’s up! Destroy the first house |
| 44% | PARTA | 5 | Form’s first section, perhaps |
| 44% | SOLOED | 6 | First time flying |
| 44% | DEBUT | 5 | First time out |
| 42% | HOMEROOM | 8 | Spot for one’s first period, perhaps |
| 42% | ELON | 4 | First name of Time's 2021 Person of the Year |
| 41% | EVER | 4 | "For the first time ___ ..." |
| 41% | SECOND | 6 | Not the first time |
| 41% | EVER | 4 | "For the first time ___" |
| 41% | BROACHED | 8 | Mentioned for first time |
| 41% | EVER | 4 | "For the first time ___..." |