| 100% | SMOKELESS | 9 | First __ powder for firearms was invented in 1884 |
| 41% | SMALLPOX | 8 | First disease for which a vaccine was invented |
| 41% | DETECTOR | 8 | The first metal __ was invented in 1874 |
| 41% | DETECTOR | 8 | The first particle __ was invented in 1911 |
| 41% | TURBINE | 7 | First successful gas __ was invented in 1903 |
| 41% | ELECTRIC | 8 | First commercial __ generator was invented in 1873 |
| 39% | GUAC | 4 | Dip that was first developed in Mexico, for short |
| 39% | TIVO | 4 | Device for recording shows that was first sold in 1999 |
| 38% | TECATE | 6 | Mexican beer named for the city it was first produced in |
| 38% | ASIA | 4 | Where the Olympics were held for the first time in 1964 |
| 38% | RADIO | 5 | It was used to play music for the first time in 1906 |
| 38% | YDS | 3 | Ten of them are needed for a first down in football: Abbr. |
| 37% | MBA | 3 | The program for obtaining this degree was first established at Harvard in 1908 |
| 37% | JOHNBROWN | 9 | *Abolitionist who was the first person executed for treason in the United States |
| 37% | SAUDIS | 6 | Women who were legally permitted to drive for the first time in 2018 |
| 37% | SMORE | 5 | The first recipe for one was published in "Tramping and Trailing With the Girl Scouts" (1927) |
| 36% | JULIANNEMOORE | 13 | Actress whose first Oscar nomination was for her role in "Boogie Nights": 2 wds. |
| 36% | ROCKY | 5 | ___, official mascot for the Denver Nuggets NBA team that was first seen in 1990 |
| 36% | METEOR | 6 | Ford ___, automobile first sold in 1949 whose name is an alias for "shooting star" |
| 36% | MICHELLEOBAMA | 13 | First Lady who sang "This Is for My Girls" with Missy Elliott in "Carpool Karaoke": 2 wds. |
| 36% | PORTLAND | 8 | Modern __ cement was invented in 1845 |
| 36% | DENMARK | 7 | Lego was invented in this country |
| 36% | PHANATIC | 8 | Phillie ___, official mascot for the Philadelphia Phillies MLB team that was first seen in 1978 |
| 36% | FREDBIRD | 8 | ___, official mascot for the St. Louis Cardinals MLB team that was first seen in 1979 |
| 35% | SSN | 3 | The first one was issued in 1936, for short |
| 35% | POCKET | 6 | __ calculator was invented in Japan in 1970 |
| 35% | GORILLA | 7 | The Suns ___, official mascot for the Phoenix Suns NBA team that was first seen in 1980 |
| 35% | BATTERY | 7 | The rechargeable lead-acid __ was invented in 1859 |
| 35% | ICEE | 4 | Beverage that was invented in a Dairy Queen |
| 35% | GERMANY | 7 | Country where contact lenses were invented in 1888 |