| 100% | DOUGWILLIAMS | 12 | First African American quarterback to be named 44-Across, in 1988: 2 wds. |
| 64% | PATRICK | 7 | With 38-Across, second African American quarterback to be named 44-Across, in 2020 |
| 49% | VENUSWILLIAMS | 13 | First African-American tennis player to be ranked #1 in women's singles during the Open Era: 2 wds. |
| 46% | JANEADDAMS | 10 | First American woman to be awarded the Nobel Peace Prize, in 1931: 2 wds. |
| 44% | ETHELWATERS | 11 | Harlem Renaissance singer and actress who was the first African American to star in her own TV show: 2 wds. |
| 43% | VENUSWILLIAMS | 13 | First African-American woman to hold the world #1 ranking in tennis's Open era: 2 wds. |
| 42% | WARRENMOON | 10 | Undrafted quarterback who was the first African American quarterback inducted into the Hall of Fame: 2 wds. |
| 40% | FAYETTEVILLE | 12 | Where Senator Hiram Rhodes Revels, first African American to serve in the U.S. Congress, was born |
| 39% | MOMSMABLEY | 10 | Trailblazing African American who was the first female comedian to perform at the Apollo Theater: 2 wds. |
| 38% | DAVIDNJOKU | 10 | Nigerian American NFL tight end who was named to his first Pro Bowl after the 2023 season: 2 wds. |
| 37% | FRANTARKENTON | 13 | Pro Football Hall of Fame quarterback who was the first pro athlete to host "Saturday Night Live," in 1977, two years after he was named the NFL MVP (2 wds.) |
| 37% | LOVIESMITH | 10 | First African-American football coach to lead a team to the Super Bowl: 2 wds. |
| 37% | MAEJEMISON | 10 | First African-American woman in space, aboard the space shuttle Endeavour in 1992: 2 wds. |
| 36% | LLOYD | 5 | Earl ___, first African American to play in the NBA |
| 36% | FRANCESARNOLD | 13 | First American woman to win the Nobel Prize in Chemistry, in 2018: 2 wds. |
| 35% | SEATTLESLEW | 11 | 1977 Triple Crown winner who was the first American champion to have been undefeated in previous races: 2 wds. |
| 35% | MICKEYMANTLE | 12 | Yankees switch-hitter who was named to the All-Century Team in 1999: 2 wds. |
| 35% | BOJACKSON | 9 | Former NFL player to be named All-Star in both football and baseball who is considered one of the greatest RBs ever: 2 wds. |
| 35% | BRAGG | 5 | Alvin ___, first African American to be elected Manhattan's district attorney |
| 35% | LUKEAIKINS | 10 | American skydiver who was the first to land safely without a parachute or wingsuit from mid-tropospheric altitude: 2 wds. |
| 35% | BOJACKSON | 9 | American athlete who has been named All-Star in baseball as well as football: 2 wds. |
| 35% | MISTYCOPELAND | 13 | First African-American prima ballerina for the American Ballet Theater: 2 wds. |
| 34% | TONIMORRISON | 12 | First African-American woman to win the Nobel Prize for Literature (2 wds.) |
| 34% | TIGERWOODS | 10 | First African-American to win golf's Masters Tournament: 2 wds. |
| 34% | SISTERSOULJAH | 13 | African American activist, novelist, and rapper with a "family" name: 2 wds. |
| 34% | MICHELLEOBAMA | 13 | First African-American woman to serve as First Lady of the United States (2 wds.) |
| 34% | ALTHEAGIBSON | 12 | First African-American woman to win the Women's Singles championship at Wimbledon (2 wds.) |
| 33% | MICHELLEOBAMA | 13 | First African-American first lady: 2 wds. |
| 33% | HARRIS | 6 | Stayce, first African American to reach three star general rank in the US Air Force (2016) |
| 33% | PATRICKMAHOMES | 14 | Chiefs quarterback who was named MVP of the 2023 Super Bowl: 2 wds. |