| 100% | PRIMORDIAL | 10 | First created |
| 86% | CHAOS | 5 | First created being, in myth |
| 81% | ADAM | 4 | First man created |
| 80% | ANN | 3 | "Raggedy" doll first created in 1915 |
| 79% | ADAM | 4 | First man ever created? |
| 78% | ULTRON | 6 | Evil robot first created by Hank Pym |
| 78% | IBUPROFEN | 9 | Painkiller first created to relieve rheumatoid arthritis |
| 78% | SSN | 3 | American ID first created in 1936: Abbr. |
| 78% | ADAM | 4 | First man created by God |
| 76% | JIGSAW | 6 | Type of puzzle first created by John Spilsbury |
| 74% | WALDORF | 7 | Salad first created at an NYC hotel in 1896 |
| 72% | RED | 3 | ___ Sonja, Marvel's fantasy comic character first created in 1973 |
| 71% | INVENT | 6 | Create for the very first time |
| 70% | MOTOROLA | 8 | Created the first cell phone in 1973 |
| 70% | ARCADE | 6 | Computer Space, first __ game created in 1971 |
| 70% | PANDORA | 7 | The first woman created in Greek Mythology |
| 68% | PANDORA | 7 | In Greek mythology, the first human woman created |
| 68% | TSAR | 4 | The first Fabergé egg was created for one |
| 68% | TIKI | 4 | The first man ever created, in Maori lore |
| 66% | SAINT | 5 | Ulrich was the first one created by a pope |
| 65% | ASA | 3 | Well-known abbr. for the chemical that Charles Frederic Gerhardt first created in 1853 |
| 63% | RABIES | 6 | Disease for which Pasteur created the first vaccine |
| 63% | LIGHT | 5 | Something created by God on the first day |
| 62% | PHOENICIA | 9 | Ancient civilization believed to have created the first alphabet |
| 60% | EPA | 3 | Org. created the same year as the first Earth Day |
| 59% | BETSY | 5 | Ross who is credited with creating the first American flag |
| 58% | POLITBURO | 9 | This first executive committee created in Russia by the Bolshevik Party in 1917 |
| 58% | EPA | 3 | Government org. created the same year as the first Earth Day |
| 56% | EPA | 3 | Government org. created the same year as the first Earth Day (Abbr.) |
| 55% | ETTA | 4 | It can go after the male first name "Henri" to create a female first name |