| 100% | MICHELLEOBAMA | 13 | First Lady who sang "This Is for My Girls" with Missy Elliott in "Carpool Karaoke": 2 wds. |
| 38% | BETTYFORD | 9 | 1970s US First Lady who was honored with a 2024 US postage stamp: 2 wds. |
| 34% | JACKIEKENNEDY | 13 | Former First Lady of the United States who was born in July (2 wds.) |
| 33% | BETTYFORD | 9 | First Lady who wrote the 1978 memoir "The Times of My Life": 2 wds. |
| 33% | CHRISMARTIN | 11 | Coldplay lead singer who sang "Viva La Vida" in "Carpool Karaoke": 2 wds. |
| 32% | HILLARYCLINTON | 14 | Former First Lady who has been on the Time 100 list 10 times: 2 wds. |
| 32% | BINGCROSBY | 10 | Crooner who sings "I've Got Plenty to Be Thankful For" in the Thanksgiving scene of 17-Across (2 wds.) |
| 32% | JILLBIDEN | 9 | Current US First Lady who was also the Second Lady from 2009 to 2017: 2 wds. |
| 31% | JIMMYFALLON | 11 | Late-night host who sings "All I Want for Christmas Is You" with Dolly Parton on "A Holly Dolly Christmas" (2 wds.) |
| 31% | GINGERROGERS | 12 | Actress who sings the title song with co-star Cornel Wilde in the 1947 film "It Had to Be You" (2 wds.) |
| 30% | DESTINYSCHILD | 13 | Girl group who sang "Survivor," with whom Beyonce started her career: 2 wds |
| 30% | EVAPERON | 8 | Actress LuPone's first Tony Award was for playing this Argentinian political leader in the 1979 Broadway musical "Evita": 2 wds. |
| 30% | ABIGAILADAMS | 12 | US First Lady from 1797 to 1801 who was also the Second Lady from 1789 to 1797: 2 wds. |
| 30% | BETTYFORD | 9 | US First Lady from 1974 to 1977 who was also the Second Lady from 1973 to 1974: 2 wds. |
| 30% | LAURABUSH | 9 | Former Girl Scout who was First Lady of the United States from 2001 to 2009 (2 wds.) |
| 30% | MICHELLEOBAMA | 13 | Former Girl Scout who was First Lady of the United States from 2009 to 2017 (2 wds.) |
| 30% | JACKBLACK | 9 | "The House with a Clock in Its Walls" actor who is also a musician and is famous for his role in "Gulliver's Travels": 2 wds |
| 30% | BETTYFORD | 9 | Former first lady who co-wrote the memoir "The Times of My Life" (2 wds.) |
| 29% | ELTONJOHN | 9 | Pop star who sang a duet with Lady Gaga on his hit "Your Song" at the 2010 Grammys: 2 wds. |
| 29% | STEVIEWONDER | 12 | "For Once in My Life" singer who was honored with a "Billboard" Icon Award in 2012 (2 wds.) |
| 29% | SMORE | 5 | The first recipe for one was published in "Tramping and Trailing With the Girl Scouts" (1927) |
| 29% | LOVER | 5 | Sing along to this 1996 Spice Girls song! "If you wanna be my ___, you gotta get with my friends..." |
| 29% | BILLYPRESTON | 12 | Singer who sang with Nat King Cole on a TV show at 11 and released his first album at 16: 2 wds. |
| 29% | MICHELLEOBAMA | 13 | Former First Lady and "Becoming" author who was on the cover of the Winter 2021/22 issue of Vogue Knitting: 2 wds. |
| 29% | DOLLYPARTON | 11 | Country music star who sang "Islands in the Stream" with 36-Across (2 wds.) |
| 28% | JILLBIDEN | 9 | Former Girl Scout who is the current First Lady of the United States (2 wds.) |
| 28% | ARIANAGRANDE | 12 | American singer/songwriter who sings "Rain on Me" with Lady Gaga on "Chromatica" (2 wds.) |
| 28% | ROSALYNNCARTER | 14 | First Lady who wrote the 1984 memoir "First Lady From Plains": 2 wds. |
| 28% | LAURABUSH | 9 | First Lady who wrote the 2010 memoir "Spoken From the Heart": 2 wds. |
| 28% | NANCYSINATRA | 12 | "These Boots Were Made for Walkin'" singer who sang on an episode of "The Sopranos": 2 wds. |