| 100% | LINC | 4 | First minicomputer designed by Wesley A. Clark and Charles Molnar: Abbr. |
| 31% | OTOE | 4 | First Indian tribe met by Lewis and Clark |
| 30% | OTOES | 5 | First tribe encountered by Lewis and Clark |
| 30% | OTOE | 4 | First tribe met by Lewis and Clark |
| 30% | OTOE | 4 | First tribe encountered by Lewis and Clark |
| 30% | IDA | 3 | Locale traversed by Lewis and Clark: Abbr. |
| 30% | NMI | 3 | Abbr. for someone with just a first and last name |
| 30% | NMI | 3 | Abbr. for someone with only a first and last name |
| 29% | DORASPENLOW | 11 | First wife of David Copperfield in a 1850 novel by Charles Dickens |
| 28% | THU | 3 | Abbr. for a word also with abbrs. by its first four or first five letters |
| 28% | THEBRIDGE | 9 | First part of a 1952 best seller's title, followed by 37- and 51-Across |
| 27% | GUNN | 4 | "Tim ___: A Guide to Quality, Taste and Style," book by TV personality and design mentor |
| 27% | POOR | 4 | Start of a word ladder whose first and last words are suggested by 36-Across |
| 26% | CAPTAIN | 7 | & 15A 1922 Derby-winning horse named after a character in Dombey and Son by Charles Dickens |
| 26% | FLIPFLOPPING | 12 | Switching positions, and a phrase spelled by the first letters of 12 words that have switched positions |
| 25% | STORMYWEATHER | 13 | Song first sung by Ethel Waters at Harlem's Cotton Club ... and a hint to four other long answers |
| 24% | EMCEE | 5 | Word shortened from a three-word phrase that can be further shortened by dropping its first, fourth and fifth letters |
| 24% | JOHN | 4 | ___ Elway, quarterback who was selected first overall draft pick by the Colts and is a 2-time Super Bowl champ |
| 24% | JIM | 3 | ___ Plunkett, quarterback who was selected first overall draft pick by the Patriots and is a 2-time Super Bowl champ |
| 24% | ZEPPELINS | 9 | Rigid airships designed by a German count |
| 24% | ESTAB | 5 | Abbr. followed by a date |
| 24% | REC | 3 | Abbr. by a blinking light |
| 24% | YDS | 3 | Abbr. by a golf tee |
| 24% | ETC | 3 | Abbr. preceded by a comma |
| 24% | TERRY | 5 | ___ Bradshaw, football quarterback who was selected first overall draft pick by the Steelers and is a 4-time Super Bowl champ |
| 24% | MEALPLAN | 8 | Regimen that might be designed by a nutritionist |
| 24% | CAMEL | 5 | "A horse designed by a committee" |
| 24% | FACTOTUM | 8 | A novel written by Charles Bukowski |
| 24% | NICKLEBY | 8 | A novel by Charles Dickens: "Nicholas __" |
| 24% | BFFS | 4 | First responders in a crisis?: Abbr. |