| 100% | GALILEO | 7 | First person to use a telescope to study space |
| 48% | URANUS | 6 | First planet discovered using a telescope |
| 48% | TESTPILOT | 9 | First person to fly a plane |
| 47% | ARTIST | 6 | Person who uses a paintbrush to create |
| 47% | ANNOUNCER | 9 | Person who uses a tannoy to provide information |
| 46% | CHRISTIAANBARNYARD | 18 | First person to perform a heart transplant on a chicken? |
| 46% | TELSTAR | 7 | First satellite to transmit a phone call through space, 1962 |
| 46% | GAGARIN | 7 | First person to travel to space |
| 46% | GUTENBERG | 9 | First to use a printing press |
| 45% | ALEKSEI | 7 | Cosmonaut Leonov, the first person to conduct a spacewalk |
| 45% | DEAN | 4 | First person to receive a posthumous Academy Award for Best Actor nomination |
| 43% | BONO | 4 | First musician to be a ''Time'' Person of the Year |
| 43% | ANGLEE | 6 | First nonwhite person to win a directing Oscar, in 2006 |
| 43% | FLIPWILSON | 10 | First Black person to host a successful TV variety show |
| 43% | EILEEN | 6 | ___ Collins, first woman to command a space shuttle |
| 43% | COLLINS | 7 | Eileen, first woman to command a space shuttle |
| 43% | TWO | 3 | Number of people needed to use a seesaw |
| 43% | MAINE | 5 | First state to use ranked-choice voting in a presidential election |
| 43% | GREGORY | 7 | __ Olsen, the third person to be a space tourist |
| 43% | TWO | 3 | Number of people needed to use a teeter-totter |
| 42% | EGYPTIANS | 9 | First ancient people known to use hieroglyphics |
| 42% | EXES | 4 | People who used to be a couple |
| 42% | JKROWLING | 9 | First person to win a Smarties Prize, for children's books, three years in a row |
| 42% | OMAR | 4 | Ilhan who was the first person to wear a hijab on the House floor |
| 42% | KELLER | 6 | Helen, first deaf-blind person to earn a BA degree |
| 42% | URANUS | 6 | First planet to be identified with a telescope |
| 42% | EXMAYOR | 7 | Person who used to lead a city (Hyph.) |
| 42% | SCHIRRA | 7 | Astronaut Wally, the first person to go into space three times |
| 41% | LEROY | 5 | Colonel ___ Cooper, first man to make a second orbital space flight |
| 41% | HELEN | 5 | ___ Keller, first deafblind person to earn a Bachelor of Arts degree |