| 100% | LEITER | 6 | First pitcher to have defeated all 30 major-league teams |
| 43% | GEHRIG | 6 | First major league player to have his number retired |
| 42% | GEHRIG | 6 | First Major League Baseball player to have his number retired |
| 41% | STLOUISCITYSC | 13 | Major League Soccer expansion team in Missouri expected to play its first game in 2023 (4 wds.) |
| 41% | SOSA | 4 | First batter to hit a home run against every Major League Baseball team |
| 40% | INDIANS | 7 | First major-league team to sign Satchel Paige |
| 39% | MARINERS | 8 | Other than the Nationals, only current Major League Baseball team never to have played in a World Series |
| 37% | TEXASRANGERS | 12 | 2023 American League wildcard team that defeated the Arizona Diamondbacks to win their first World Series title (2 wds.) |
| 36% | USA | 3 | Home country for 29 of 30 Major League baseball teams: Abbr. |
| 35% | KAZMATSUI | 9 | First Japanese infielder to sign with a major-league team, familiarly |
| 35% | SARAZEN | 7 | First golfer to win all four majors |
| 32% | LYLE | 4 | Pitcher Sparky, first American League reliever to win the Cy Young Award |
| 32% | NHL | 3 | Sports league whose first four teams were all Canadian: Abbr. |
| 32% | JIMTHORPE | 9 | Only Olympic gold medalist to have played Major League Baseball and National Football League: 2 wds. |
| 31% | REDS | 4 | Major league team from Cincinnati |
| 31% | REDS | 4 | Cincinnati major league team |
| 30% | YDS | 3 | A football team has to gain ten of them for a first down: Abbr. |
| 30% | NOLANRYAN | 9 | Only pitcher to have his number retired by three teams (#30, Angels, 1992; #34, Astros, 1996; #34, Rangers, 1996): 2 wds. |
| 30% | STARTER | 7 | First pitcher to pitch in a ball game |
| 30% | SYRIA | 5 | First Arab country to have sanctions imposed on it by the Arab League |
| 29% | TOR | 3 | Only Canadian major league team, on scoreboards |
| 29% | ERA | 3 | Major league pitcher's stat: Abbr. |
| 29% | ASTRODOME | 9 | Major League's first roofed stadium |
| 29% | ASTROS | 6 | Major League Baseball team in Houston |
| 29% | GEORGIA | 7 | Team that defeated 15-Across to win the 2022 College Football Playoff National Championship, its first national title since 1980 |
| 28% | CARRIESNOWEIGHT | 15 | Has little significance ... and to all intents and purposes, what the first word of 17-, 27- and 48-Across does |
| 28% | THROWACURVEBALL | 15 | Candy Cummings was the first pitcher to do this |
| 28% | ASTROS | 6 | Major league baseball team in Houston, Texas |
| 28% | RAYS | 4 | Major League Baseball team from Tampa Bay |
| 28% | TYLER | 5 | First president to have a veto overridden |