| 100% | APPLAUSE | 8 | First single from "ARTPOP" |
| 78% | WHEREAREWENOW | 13 | First single from 44-Across: 4 wds. |
| 74% | BLACKOR | 7 | __ White; first single from MJ's Dangerous album |
| 74% | LOVESTORY | 9 | Taylor Swift's first single from Fearless album |
| 69% | HAM | 3 | First single from Jay-Z and Kanye West's album "Watch the Throne" (2011) |
| 62% | VICTORY | 7 | Hit single from 53-Across's Grammy-winning first album "No Way Out" |
| 60% | NEWKIDINTOWN | 12 | Grammy-winning song by the Eagles which was the first single from the same album as 15a: 4 wds. |
| 60% | BEVERLYHILLS | 12 | Single from the album "Make Believe" that was 42-Across's first Top 10 hit (2 wds.) |
| 59% | TORN | 4 | First official single from LeToya's debut album released in 2006 |
| 59% | LOOKWHATYOU | 11 | "___ Made Me Do," the first single from 16a that was released late August and is a huge hit: 3 wds. |
| 56% | CLOSER | 6 | Hit single from The Chainsmokers, featuring Halsey, which became their first #1 song on the Billboard Hot 100 |
| 55% | TITLETRACK | 10 | First single, often |
| 53% | YEAH | 4 | Single from Usher's "Confessions" |
| 53% | LOVEMEDO | 8 | Beatles' first single |
| 52% | LOVEMEDO | 8 | First single released by the Beatles |
| 52% | YEAH | 4 | Single from Usher's "Confessions" album |
| 52% | SOS | 3 | Single from the 1975 album "ABBA" |
| 50% | HEYJOE | 6 | Jimi Hendrix's first single |
| 50% | LOVEMEDO | 8 | The Beatles' first single, 1962 |
| 50% | HUMBLE | 6 | Chart-topping single from "DAMN." |
| 50% | BRAVE | 5 | Lead single from 15-Across |
| 50% | APRIORI | 7 | From first principles |
| 49% | TANGLEDUPINBLUE | 15 | Single from Dylan's "Blood on the Tracks" |
| 49% | EMI | 3 | Producer of the Beatles' first single |
| 49% | RADIO | 5 | "___ Free Europe" (REM's first single) |
| 49% | PRETTY | 6 | __ Vacant, Sex Pistols single from 1977 |
| 49% | ONLYGIRL | 8 | Lead single from Rihanna's "Loud" |
| 49% | YMCA | 4 | 1978 single from the album "Cruisin'" |
| 49% | SIDEA | 5 | Single’s first half |
| 48% | LAURA | 5 | First lady from Texas |