| 100% | BANNISTER | 9 | First to run a mile in under 4 minutes: Roger __ |
| 60% | BANNISTER | 9 | Roger, first athlete to run a 4-minute mile |
| 59% | RYUN | 4 | Jim ___, athlete who was the first high school junior to run a mile in under four minutes |
| 54% | MILE | 4 | Roger Bannister was the first to run it in under four minutes |
| 53% | BANNISTER | 9 | Roger —, first man to run a sub-four minute mile |
| 44% | JIMHINES | 8 | First to run 100m in under 10 seconds, died 2023 |
| 34% | XXXXXX | 6 | Ready to run, in a way |
| 34% | LOAD | 4 | Carbo-___ (prepare to run a marathon, in a way) |
| 33% | SERIESI | 7 | First group in a product run |
| 33% | EVELYNASHFORD | 13 | The first track and field athlete to run 100 meters under 11 seconds in an Olympic Games and who has won a total of 5 Olympic medals: 2 wds. |
| 33% | MILE | 4 | Difficult-but-possible distance to run in four minutes |
| 33% | TIRE | 4 | Start to run out of gas, in a sense |
| 33% | DASH | 4 | Run to somewhere in a great hurry |
| 33% | DDE | 3 | First POTUS to ride in a helicopter |
| 33% | DEAR | 4 | First word in a letter to Santa |
| 32% | SOUP | 4 | First in a group leader to 28-Down |
| 32% | TEN | 3 | First number in boxing countdown to a knockout |
| 32% | LISALESLIE | 10 | First player to dunk in a WNBA game |
| 32% | ASTROS | 6 | First baseball team to play in a dome |
| 32% | STARTER | 7 | First pitcher to pitch in a ball game |
| 32% | PASS | 4 | Alternative to a run, in football |
| 32% | CLOSEBUTNOCIGAR | 15 | Words to a first runner-up |
| 32% | MARIS | 5 | Roger who set a home run record in 1961 |
| 32% | HST | 3 | First U.S. pres. to travel in a submarine |
| 31% | AQUAJOG | 7 | Run in a pool, perhaps to train for a marathon |
| 31% | TRICKLE | 7 | To drip or run down in a small flowing stream |
| 31% | LISALESLIE | 10 | First woman to dunk in a WNBA game: 2 wds. |
| 31% | PALM | 4 | Co. that was the first to successfully market a PDA worldwide in 1997 |
| 31% | JACKSON | 7 | First president to have running water in the White House (1833) |
| 31% | RBI | 3 | In baseball, the plays that allow a run to be scored |