| 100% | APPLE | 5 | First U.S. company to be valued at $1 trillion |
| 95% | APPLE | 5 | First public U.S. company to be valued at $1 trillion |
| 82% | APPLE | 5 | First company to be valued at $1 trillion |
| 46% | IKEA | 4 | Company that was the first in the U.S. to air a TV ad with a gay couple (1994) |
| 39% | IKEA | 4 | First company to feature a gay couple in a mainstream U.S. TV ad (1994) |
| 39% | ABE | 3 | Nickname of the first US president to be assassinated |
| 37% | TAFT | 4 | First president to be buried at Arlington National Cemetery |
| 37% | VERMONT | 7 | First U.S. state to abolish slavery |
| 37% | NIXON | 5 | First U.S. President to visit China |
| 37% | SMASHCAKE | 9 | Sweet treat meant to be destroyed at a 1-year-old's birthday party |
| 37% | PENNY | 5 | First U.S. coin to feature a president |
| 37% | STLOUIS | 7 | First U.S. city to host the Olympics |
| 37% | GLENN | 5 | First U.S. astronaut to circle the earth |
| 36% | OBERLIN | 7 | First U.S. college to award degrees to women |
| 36% | HST | 3 | First U.S. pres. to travel in a submarine |
| 36% | BURR | 4 | First U.S. vice president not to become president |
| 36% | STLOUIS | 7 | First U.S. city to host the Olympic Games |
| 36% | STL | 3 | First U.S. city to host the Olympics (Abbr.) |
| 36% | YALE | 4 | First U.S. university to award a Ph.D. |
| 36% | STL | 3 | First U.S. city to host the Olympic Games |
| 36% | RITAORA | 7 | Pop star whose first U.K. No. 1 hit was “How We Do (Party)” |
| 36% | MEIR | 4 | First U.S. citizen to become Israel’s P.M. |
| 36% | HAMPSHIRE | 9 | First U.S. college to divest from apartheid South Africa |
| 36% | DETROIT | 7 | First U.S. city to pave a road for cars |
| 36% | JACKSON | 7 | First US President to be the target of an assassination attempt (which failed), on January 30, 1835 |
| 35% | LIL | 3 | ___ Wayne, who was signed to his first label at age eleven |
| 35% | PENNY | 5 | First U.S. coin to feature a real person’s image |
| 35% | MAHALIA | 7 | Jackson who was the first gospel singer to perform at Carnegie Hall |
| 34% | ARTHURASHE | 10 | Winner of the first US Open Men's Singles championship (1968), for whom the largest stadium at the USTA National Tennis Center is named (2 wds.) |
| 34% | RENO | 4 | Janet who was the first woman to serve as U.S. attorney general |