| 100% | IDALUPINO | 9 | First woman to direct a film noir (1953's "The Hitch-Hiker") |
| 62% | IDA | 3 | ___ Lupino, first woman to direct a classic noir film |
| 58% | JULIEDASH | 9 | First black woman to direct a feature-length film distributed theatrically in the United States |
| 51% | YENTL | 5 | Film for which Barbra Streisand became the first woman to win a Golden Globe for directing |
| 44% | RETTON | 6 | First woman to appear on the front of a Wheaties box |
| 43% | FROMTHEROUGH | 12 | 2014 film starring Taraji P. Henson as the first woman to coach a men's golf team (3 wds.) |
| 43% | LESLEYVISSER | 12 | First woman to report from the sidelines for a Super Bowl game (2 wds.) |
| 43% | ANN | 3 | ___ Compton, first woman to cover the White House for a TV network |
| 42% | UTA | 3 | ___ Pippig, first woman to win the Boston Marathon three times in a row |
| 42% | FDR | 3 | First prez to appoint a woman to the cabinet |
| 42% | EDITH | 5 | Wharton, the first woman to win a Pulitzer |
| 42% | AMYMCGRATH | 10 | First woman to fly an F/A-18 in combat for the U.S. Marine Corps |
| 41% | HARRIETQUIMBY | 13 | First woman to earn a pilot's license in the United States and the first woman to fly across the English Channel (2 wds.) |
| 41% | NORMA | 5 | Woman's name that becomes a man's name when its first letter is added to the end |
| 41% | CURIE | 5 | Surname of the first woman to win a Nobel prize |
| 40% | MARIE | 5 | First name of the first woman to win a Nobel Prize |
| 40% | MIRAINAGASU | 11 | First American woman to land a triple axel at the Olympics |
| 40% | ROSAPARKS | 9 | First woman to lie in honor in the U.S. Capitol |
| 40% | LOCKER | 6 | Best Film Oscar, directed by a woman, The Hurt __ |
| 40% | MEYERS | 6 | Ann ___, first woman to sign with the N.B.A. |
| 39% | ALYSSANAKKEN | 12 | First woman to coach on the field of a Major League Baseball game, for the San Francisco Giants in 2020: 2 wds. |
| 39% | THEPIANO | 8 | First Palme d'Or-winning film directed by a woman (1993) |
| 38% | DAWN | 4 | ___ Braid, first woman to hold a full-time coaching job in the National Hockey League |
| 38% | EDITH | 5 | Wharton who was the first woman to win a Pulitzer Prize for fiction |
| 38% | DOMEE | 5 | Shi who was the first woman to have the sole director’s credit on a Pixar feature, for “Turning Red” |
| 38% | KATIESOWERS | 11 | First woman in the NFL to coach in a Super Bowl, for the San Francisco 49ers in 2020: 2 wds. |
| 38% | EDERLE | 6 | First woman to swim the English Channel |
| 38% | CURIE | 5 | First woman to teach at the Sorbonne |
| 38% | CURIE | 5 | First woman to win the Nobel Prize |