| 100% | LIZCAMBAGE | 10 | First woman to dunk in an Olympic basketball game: 2 wds. |
| 67% | LISALESLIE | 10 | First woman to dunk in a WNBA game: 2 wds. |
| 59% | BECKYHAMMON | 11 | First woman to act as head coach in an NBA game, for the San Antonio Spurs in 2020: 2 wds. |
| 54% | BRITTNEYGRINER | 14 | First player to dunk twice in a WNBA game: 2 wds. |
| 52% | LISALESLIE | 10 | Basketball Hall of Fame inductee who was the first player to dunk in a WNBA game: 2 wds. |
| 50% | ALYSSANAKKEN | 12 | First woman to coach on the field of a Major League Baseball game, for the San Francisco Giants in 2020: 2 wds. |
| 49% | BRITTNEYGRINER | 14 | First WNBA player to dunk twice in one game: 2 wds. |
| 48% | DANICAPATRICK | 13 | First woman to win an IndyCar event: 2 wds. |
| 45% | DANICAPATRICK | 13 | Racing great who became the first woman driver to win an Indy car race in April 2008 (2 wds.) |
| 43% | MARGARETCOURT | 13 | Australian tennis player who was the first woman to win the Grand Slam in the Open Era: 2 wds. |
| 42% | LESLEYVISSER | 12 | First woman to report from the sidelines for a Super Bowl game (2 wds.) |
| 42% | KATIESOWERS | 11 | First woman in the NFL to coach in a Super Bowl, for the San Francisco 49ers in 2020: 2 wds. |
| 41% | FRANCESARNOLD | 13 | First American woman to win the Nobel Prize in Chemistry, in 2018: 2 wds. |
| 41% | JANEADDAMS | 10 | First American woman to be awarded the Nobel Peace Prize, in 1931: 2 wds. |
| 41% | LISALESLIE | 10 | First player to dunk in a WNBA game |
| 41% | EVELYNASHFORD | 13 | The first track and field athlete to run 100 meters under 11 seconds in an Olympic Games and who has won a total of 5 Olympic medals: 2 wds. |
| 41% | DANICAPATRICK | 13 | First woman to lead the Indy 500: 2 wds. |
| 40% | RONDA | 5 | Rousey, first American woman to win an Olympic medal in judo |
| 39% | JANETRENO | 9 | First woman to serve as attorney general of the US: 2 wds. |
| 39% | AMELIAEARHART | 13 | First woman to fly solo across the Atlantic Ocean: 2 wds. |
| 39% | SANDIEGOWAVEFC | 14 | National Women's Soccer League expansion team in California expected to play its first game in 2022 (4 wds.) |
| 39% | BESSIECOLEMAN | 13 | First woman of African-American and Native American descent to earn an international pilot's license (2 wds.) |
| 39% | SARAHPALIN | 10 | In 2006, she became the first woman to be elected governor of Alaska: 2 wds. |
| 38% | ALICIAKEYS | 10 | "Girl on Fire" singer/pianist who was the first woman to have an "MTV Unplugged" album debut at #1 (2 wds.) |
| 38% | SUSANAMARTINEZ | 14 | In 2010, she became the first woman to be elected governor of New Mexico: 2 wds. |
| 38% | NIKKIHALEY | 10 | In 2010, she became the first woman to be elected governor of South Carolina: 2 wds. |
| 38% | HARRIETQUIMBY | 13 | First woman to earn a pilot's license in the United States and the first woman to fly across the English Channel (2 wds.) |
| 38% | OTTO | 4 | Kristin ___, first woman to win six gold medals at a single Olympic games |
| 38% | HELENHAYES | 10 | First (and oldest) woman to achieve an EGOT (2 wds.) |