| 100% | DEVRY | 5 | For-profit university with dozens of U.S. campuses |
| 43% | MISSISSIPPIRIVERBASIN | 21 | Watershed draining dozens of U.S. states |
| 42% | TYLER | 5 | City with a University of Texas campus |
| 41% | AUS | 3 | Country with the University of Melbourne, for short |
| 40% | KEYS | 4 | Locale for the southernmost part of U.S. Route 1, with "the" |
| 40% | NONE | 4 | Number of U.S. states starting with "B" |
| 39% | ONE | 3 | Number of U.S. states with three-word capitals |
| 39% | THREE | 5 | Number of U.S. states that start with "C" |
| 39% | DEPT | 4 | The "D" of U.S.D.A., for short |
| 39% | THREE | 5 | Number of U.S. Open wins for Tiger Woods |
| 39% | FIRESIGN | 8 | Comedy troupe, ___ Theatre, with dozens of albums released in the 70's |
| 39% | ONE | 3 | Number of U.S. states that start with a D |
| 39% | OKLA | 4 | U.S. state with a panhandle, for short |
| 39% | CAL | 3 | U.S. state with San Diego, for short |
| 39% | FDR | 3 | U.S. pres. for most of 55-Down |
| 38% | STPETE | 6 | Guinness record holder for the U.S. city with the most consecutive days of sun (768), informally |
| 38% | TWO | 3 | Number of U.S. state names that start with a V |
| 38% | NEWBURNSWICK | 12 | U.S. city with a lot of candle shops? |
| 38% | ASTROTURF | 9 | U.S. brand of synthetic grass for sports fields |
| 38% | KEN | 3 | Doll with dozens of professions |
| 38% | CHAMPAIGN | 9 | City in Illinois, US, home to the University of Illinois with sister city Urbana |
| 37% | ALASKA | 6 | U.S. state with the highest percentage of Native residents |
| 37% | ALASKA | 6 | U.S. state with nearly 34,000 miles of shoreline |
| 37% | CNN | 3 | U.S. broadcaster of Have I Got News for You |
| 37% | TOWNANDGOWN | 11 | Of a university's relationship with its surroundings |
| 37% | NEB | 3 | Midwestern U.S. state with Omaha, for short |
| 37% | MALL | 4 | Place with dozens of chain stores |
| 37% | ENERGY | 6 | U.S. Department of ___ (org. with a windmill on its seal) |
| 37% | LABOR | 5 | U.S. Department of ___ (org. with an anvil on its seal) |
| 37% | IVAN | 4 | With 21-Across, U.S. Open champ of 1985-87 |