| 100% | JONLOVITZ | 9 | Former Groundlings comedian who played pathological liar Tommy Flanagan on "SNL": 2 wds. |
| 62% | WILLFORTE | 9 | Former Groundlings comedian who played MacGruber on "SNL": 2 wds. |
| 62% | KRISTENWIIG | 11 | Former Groundlings comedian who played Target Lady on "SNL": 2 wds. |
| 62% | PHILHARTMAN | 11 | Former Groundlings comedian who played Anal-Retentive Chef on "SNL": 2 wds. |
| 40% | FREDDIEPRINZE | 13 | Stand-up comedian who played young mechanic Chico on "Chico and the Man": 2 wds. |
| 39% | ANDYSAMBERG | 11 | Former "SNL" comedian who stars on a sitcom set in an NYPD precinct: 2 wds. |
| 38% | CAROLBURNETT | 12 | Emmy-winning comedian who played a clumsy woman with a guardian angel on "The Twilight Zone": 2 wds. |
| 38% | FLIPWILSON | 10 | Stand-up comedian who played Geraldine on his Emmy-winning variety show from 1970 to 1974: 2 wds. |
| 38% | MARTINFREEMAN | 13 | "Sherlock" actor who plays former CIA agent Everett Ross on "Secret Invasion": 2 wds. |
| 38% | DANNYMCBRIDE | 12 | "Vice Principals" actor who played a former pro baseball player on "Eastbound & Down": 2 wds. |
| 38% | JONBARINHOLTZ | 13 | "Superstore" actor who plays Wesley Payne, grandson of the former CEO, on "American Auto": 2 wds. |
| 37% | DAMIANMCGINTY | 13 | Irish singer who played Rory Flanagan on "Glee" and was a member of 32-Across: 2 wds. |
| 37% | TIFFANYHADDISH | 14 | "Girls Trip" actress who plays Tray's married former girlfriend on "The Last O.G.": 2 wds. |
| 37% | JERRYSEINFELD | 13 | Comedian who played a fictional version of himself on a sitcom about "nothing" (2 wds.) |
| 37% | TONYDANZA | 9 | "The Good Cop" actor who played a former pro baseball player on "Who's the Boss?": 2 wds. |
| 36% | WANDASYKES | 10 | Stand-up comedian who plays a fictionalized version of herself on "Curb Your Enthusiasm" (2 wds.) |
| 36% | RICHARDLEWIS | 12 | Stand-up comedian who plays a fictionalized version of himself on "Curb Your Enthusiasm" (2 wds.) |
| 35% | COBIESMULDERS | 13 | "Stumptown" actress who plays former S.H.I.E.L.D. agent Maria Hill on the Disney+ series "Secret Invasion": 2 wds. |
| 35% | TIMOTHYDALTON | 13 | Former James Bond portrayer who played Sir Malcolm Murray on 21-Across: 2 wds. |
| 35% | LAURALEIGHTON | 13 | "Pretty Little Liars" actress who played Sydney Andrews on "Melrose Place": 2 wds. |
| 35% | TARANKILLAM | 11 | Former "Saturday Night Live" regular who plays Will on 31-Across: 2 wds. |
| 35% | LILYJAMES | 9 | "Downton Abbey" actress who plays Pamela Anderson on the Hulu series "Pam & Tommy" (2 wds.) |
| 35% | GABYHOFFMANN | 12 | "Girls" actress who plays former Forum general manager Claire Rothman on "Winning Time" (2 wds.) |
| 34% | SEBASTIANSTAN | 13 | "The Falcon and the Winter Soldier" actor who plays Tommy Lee on "Pam & Tommy" (2 wds.) |
| 34% | RYANPHILLIPPE | 13 | "Damages" and "Shooter" actor who plays a former cop on 1-Across/65-Across (2 wds.) |
| 34% | FREDARMISEN | 11 | Former "Saturday Night Live" comedian who cocreated and frequently appears on 34-Across: 2 wds. |
| 34% | TIGNOTARO | 9 | Comedian who plays a radio host in the Amazon series "One Mississippi": 2 wds. |
| 34% | TOMCAVANAGH | 11 | Former "Ed" actor who plays Harrison Wells on "The Flash" (2 wds.) |
| 34% | PETEDAVIDSON | 12 | Comedian on 29-Down who plays Scott in "The King of Staten Island": 2 wds. |
| 34% | KRISTENSCHAAL | 13 | Comedian who voices Louise Belcher on "Bob's Burgers": 2 wds. |