| 100% | KYOTO | 5 | Former Japanese capital that was the setting for the ___ Protocol, a 1997 agreement |
| 46% | PALAU | 5 | Micronesian island that was the setting for a season of "Survivor" |
| 43% | LAKE | 4 | ___ Wallenpaupack, water body in Scranton that was the setting for a Dunder Mifflin cruise party in "The Office" |
| 41% | TROY | 4 | Ancient Greek city that was the setting for the Trojan War |
| 40% | BEDROCK | 7 | Fictional prehistoric town that is the setting for "The Flintstones" |
| 40% | INN | 3 | Type of establishment that was the setting for "Newhart" |
| 39% | KYOTO | 5 | City that a 1997 agreement was named after that's been subsequently signed by 192 parties — but not the US |
| 39% | YORK | 4 | New New ___, fictional futuristic city that is the setting for "Futurama" |
| 39% | BOOGIE | 6 | "___ Nights," 1997 period comedy-drama about a nightclub dishwasher that is set in the disco era |
| 39% | MIT | 3 | Science-focused school that was the setting for "Good Will Hunting": Abbr. |
| 39% | FIJI | 4 | South Pacific island nation that was the setting for "Survivor" season 14 |
| 38% | ARLEN | 5 | Fictional town in Texas that is the setting for "King of the Hill" |
| 38% | MANGA | 5 | Japanese comics that are often used as the basis for anime |
| 38% | ONCE | 4 | "___ Upon a December," 1997 Liz Callaway song from the movie "Anastasia" that was nominated for a Golden Globe |
| 38% | ALTAMONT | 8 | Former California speedway that was the site of a 1969 rock concert |
| 38% | NASSAU | 6 | World capital that's a setting for three Bond films |
| 38% | NESTEGGS | 8 | Funds that are set aside for the future: 2 wds. |
| 37% | GONDOR | 6 | Middle-earth kingdom that is the setting for "The Lord of the Rings: The Return of the King" |
| 37% | MOE | 3 | The Simpson's bartender that is a homophone for 27d |
| 37% | ORIENTEXPRESS | 13 | Train that's the setting for murder in a 2017 remake directed by Kenneth Branagh (2 wds.) |
| 37% | WRATH | 5 | "The Grapes of ___," novel by John Steinbeck, set in the Great Depression, that was a major reason for him winning the Nobel Prize |
| 37% | PALM | 4 | Co. that was the first to successfully market a PDA worldwide in 1997 |
| 37% | ELMTREE | 7 | A tree that is the state symbol for Massachusetts: 2 wds. |
| 37% | MOW | 3 | Trim the lawn that is a homophone for 27a |
| 36% | BONN | 4 | German city that was a capital during the Cold War |
| 36% | HILLTOP | 7 | Summit that is the starting spot for a toboggan ride |
| 36% | ARM | 3 | Body part that might be the place for a vaccination |
| 36% | WONDERLAND | 10 | Fantasy world that is the setting for Alice's adventures, and also for 34a, 45a, 5d, 33d, and 39d |
| 36% | DEVON | 5 | English county that's the setting for Agatha Christie's "And Then There Were None" |
| 36% | EBB | 3 | With 15-Across, 1953 song that was a hit for the Righteous Brothers in 1965 |