| 100% | BLERIOT | 7 | French pilot, the first to cross the Channel |
| 68% | BLERIOT | 7 | Louis __, 1st pilot to cross the English Channel |
| 61% | FOOTING | 7 | First-__, be the first to cross the threshold |
| 60% | MAGELLAN | 8 | First to cross the Pacific |
| 60% | WON | 3 | Was the first to cross the finish line |
| 56% | DESOTO | 6 | First European to cross the Mississippi |
| 56% | MAGELLAN | 8 | First European explorer to cross the Pacific |
| 55% | MAGELLAN | 8 | First European in history to cross the Pacific |
| 55% | KRONFELD | 8 | Robert —, Austria-born sailplane designer; first pilot to fly a glider across the English Channel |
| 55% | RIGHTOFWADE | 11 | Entitlement to cross the stream first? |
| 54% | CHUCK | 5 | US pilot Yeager, first to break the sound barrier |
| 53% | HARRIETQUIMBY | 13 | First woman to earn a pilot's license in the United States and the first woman to fly across the English Channel (2 wds.) |
| 53% | STPIERRE | 8 | The first pope, to French speakers |
| 53% | HERNANDO | 8 | With 126-Across, first European to cross the Mississippi |
| 53% | EDERLE | 6 | First woman to swim the English Channel |
| 52% | EDERLE | 6 | Gertrude __, the first woman to swim the Channel |
| 52% | EARHART | 7 | First woman to earn the Distinguished Flying Cross |
| 52% | EDERLE | 6 | Gertrude ___, first woman to swim the English Channel |
| 52% | QUIMBY | 6 | Harriet, first woman to fly the English Channel |
| 51% | BLERIOT | 7 | Louis —, French aviator who made the first flight across the English Channel |
| 50% | YEAGER | 6 | Chuck, first pilot to break the sound barrier |
| 50% | SOMME | 5 | French river to the English Channel |
| 50% | ORNE | 4 | French river to the English Channel |
| 50% | NORTHWESTPASSAGE | 16 | The SS Manhattan was the first commercial ship to cross it |
| 50% | EDERLE | 6 | Gertrude ___, the first woman to swim the English Channel |
| 49% | WEBB | 4 | Matthew —, steamship captain; first man to swim the English Channel |
| 48% | NOTRE | 5 | French word that becomes its own opposite by changing the first letter to V |
| 48% | CHUCKYEAGER | 11 | First pilot to travel faster than the speed of sound |
| 47% | NAOMAMPBELL | 11 | First Black model to appear on the cover of French Vogue |
| 46% | SWAM | 4 | Crossed the Channel |