| 100% | NESTEGGS | 8 | Funds that are set aside for the future: 2 wds. |
| 52% | NEST | 4 | ___ egg (money that's set aside for the future) |
| 47% | MELALLEN | 8 | Sportscaster for the Yankees who was known for his line "How about that?!": 2 wds. |
| 47% | GREYSANATOMY | 12 | ABC's medical drama TV series starring Ellen Pompeo that is set in the fictional Seattle Grace Hospital: 2 wds. |
| 47% | GOODOMEN | 8 | Favorable sign for the future: 2 wds. |
| 45% | COTTONEYEDJOE | 13 | Traditional American folk song that was the inspiration for a 1994 hit by Swedish band Rednex: 2 wds., hyph. |
| 45% | ELMTREE | 7 | A tree that is the state symbol for Massachusetts: 2 wds. |
| 44% | KILLBILL | 8 | 2022 SZA song that was #1 on the Hot R&B/Hip-Hop charts for 21 weeks, a record: 2 wds. |
| 44% | LABOHEME | 8 | Opera by Puccini that is the basis for the film "Rent" (2 wds) |
| 44% | LADYMARMALADE | 13 | A popular song that was covered by Christina Aguilera, Lil' Kim, Mya and Pink for the soundtrack of "Moulin Rouge!": 2 wds. |
| 42% | RAPGOD | 6 | 37-Across song that was nominated for the 2015 Best Rap Performance Grammy Award (2 wds.) |
| 42% | KILLINGFLOOR | 12 | Debut novel by 25-Across that was the basis for the first season of "Reacher" (2 wds.) |
| 42% | BIGSUR | 6 | California coastal region that is the backdrop for much of HBO's "Big Little Lies" (2 wds.) |
| 42% | THEDUSTBOWL | 11 | 2012 documentary by 43-Across that was set in the 1930s: 3 wds. |
| 41% | EWINGOIL | 8 | Company that was the focus of "Dallas": 2 wds. |
| 41% | SPORTCLIMBING | 13 | Discipline that will be a medal event for the first time at the 38-Across Olympics (2 wds.) |
| 41% | INN | 3 | Type of establishment that was the setting for "Newhart" |
| 41% | WEIRDSCIENCE | 12 | Oingo Boingo single that was the theme song for a 1980s film and 1990s TV series (2 wds.) |
| 41% | BEDROCK | 7 | Fictional prehistoric town that is the setting for "The Flintstones" |
| 41% | IFSO | 4 | "Should that be the case ...": 2 wds. |
| 41% | TROY | 4 | Ancient Greek city that was the setting for the Trojan War |
| 41% | SAMADAMS | 8 | Nickname for the beer company that makes Boston Lager: 2 wds. |
| 41% | YORK | 4 | New New ___, fictional futuristic city that is the setting for "Futurama" |
| 41% | PALAU | 5 | Micronesian island that was the setting for a season of "Survivor" |
| 41% | ASEPARATION | 11 | 2011 family drama that was the first Iranian film to win an Oscar for Best Foreign Language Film (2 wds.) |
| 40% | MIT | 3 | Science-focused school that was the setting for "Good Will Hunting": Abbr. |
| 40% | SANFRANCISCO | 12 | West Coast city that will host the 2025 Laver Cup: 2 wds. |
| 40% | FIJI | 4 | South Pacific island nation that was the setting for "Survivor" season 14 |
| 40% | HOTPINK | 7 | Album by 50-Across that was nominated for Favorite Soul/R&B Album at the 2020 American Music Awards (2 wds.) |
| 40% | PLANON | 6 | Set aside time for (2 wds.) |