| 100% | RAYMAN | 6 | Game franchise with Raving Rabbids spin-off |
| 47% | CSI | 3 | Forensics franchise with a "Cyber" spin-off |
| 46% | CSI | 3 | Franchise with a short-lived "Cyber" spin-off |
| 45% | CSI | 3 | TV franchise with a Vegas spin-off |
| 45% | NCIS | 4 | Military TV franchise with three spin-offs |
| 44% | CARS | 4 | Disney/Pixar franchise with the spin-off Planes |
| 42% | TEMPLERUN | 9 | Video game franchise with evil chaser monkeys |
| 42% | DRAGONQUEST | 11 | Video game franchise with fire-breathing creatures |
| 42% | STARTREK | 8 | Sci-fi franchise with a "Strange New Worlds" spin-off: 2 wds. |
| 42% | CSI | 3 | American TV franchise with the spin-offs "Miami," "NY" and "Cyber": Abbr. |
| 41% | HALO | 4 | Sci-fi video game franchise with militaristic aliens |
| 41% | MYST | 4 | Video game franchise with the main character Atrus |
| 41% | THESIMS | 7 | Video game franchise with the cheat code "rosebud" |
| 40% | CSI | 3 | Franchise with a ''Hard Evidence'' video game |
| 39% | GTA | 3 | Popular game franchise with "Vice City" and "San Andreas" installments: Abbr. |
| 39% | WHEELOFFORTUNE | 14 | Game show with Free Spins |
| 38% | SEGA | 4 | Gaming company with the Yakuza franchise |
| 37% | BOPIT | 5 | Game with twisting, pulling, flicking and spinning |
| 37% | DOMINOS | 7 | Fast-food franchise with a game piece in its logo |
| 36% | ROULETTE | 8 | Casino game with a spinning wheel |
| 36% | SEGA | 4 | Game company with the Virtua Fighter and Yakuza franchises |
| 36% | TABOO | 5 | Hasbro game with five off-limits words |
| 36% | TABOO | 5 | Hasbro game with an off-limits word |
| 36% | MARIOBROS | 9 | Video game franchise with characters found at the ends of 17-, 20-, 53- and 58-Across |
| 36% | STARWARS | 8 | Sci-fi franchise with the new spin-off TV series, 38-Across: 2 wds. |
| 35% | BEARS | 5 | N.F.L. franchise with the most overall games played (1,472) |
| 35% | SQUASH | 6 | Game of bouncing a ball off a wall with racquets |
| 35% | NCIS | 4 | TV franchise spun off from "JAG" |
| 34% | ROULETTE | 8 | Casino game with a ball on a spinning wheel |
| 34% | ROULETTE | 8 | Casino game with a large wheel spun by a croupier |