| 100% | TOPAZ | 5 | Gemstone that was once believed to increase body heat to relieve colds and fevers |
| 36% | FLEABANE | 8 | Daisylike flower that was once believed to repel insects |
| 36% | SEAAIR | 6 | Atmosphere that was once believed to help cure tuberculosis |
| 34% | SHEA | 4 | Stadium that was once home to the Mets and the Jets |
| 33% | OMNI | 4 | Bygone Atlanta coliseum that was once home to the Flames and the Hawks |
| 33% | JADE | 4 | Green gemstone that is believed to bring good luck |
| 32% | ENDERMIC | 8 | Acting through the skin, as medicines that were once used to treat rheumatism and arthritis |
| 30% | LIP | 3 | Body part that gloss and balm may be applied to |
| 29% | CAT | 3 | Tortoiseshell ___, feline with a colorful coat that is believed to bring good luck and money |
| 29% | OSLO | 4 | Capital that was once home to Vikings |
| 29% | FOOT | 4 | Rabbit's ___, amulet believed to bring good luck that was once gifted to President Theodore Roosevelt |
| 29% | GOBI | 4 | Desert that was once home to Tarbosaurus bataar |
| 29% | FLATBUSH | 8 | Neighborhood that was once home to Ebbets Field |
| 29% | FOUR | 4 | ___-leaf clover, rare leaf that is believed to bring good luck and is used by Alfa Romeo |
| 28% | PERU | 4 | Country that was once home to the Incan Empire |
| 28% | PERU | 4 | Country that was once home to the Inca Empire |
| 28% | MAURITIUS | 9 | Island that was once home to the extinct dodo bird |
| 28% | OREM | 4 | City that was once home to the Osmonds' TV studio |
| 28% | MAURITIUS | 9 | African nation that was once home to the dodo bird |
| 28% | IVORY | 5 | Material that was once carved to make Chinese puzzle balls |
| 28% | TULSA | 5 | Oklahoma city that was once home to "Black Wall Street" |
| 28% | IVORY | 5 | Off-white material that was once carved to make netsuke |
| 28% | EASTEND | 7 | Area of London that was once home to many dockworkers |
| 28% | TULSA | 5 | Southern city that was once home to Black Wall Street |
| 28% | PERU | 4 | South American country that was once home to the Incan Empire |
| 27% | EARL | 4 | ___ Grey tea, type of black tea that's been flavored with oil of bergamot and is believed to boost heart health |
| 27% | AARE | 4 | River that loops around a once medieval city believed to have been founded in 1191 by Berthold V, Duke of Zähringen |
| 27% | MALARIA | 7 | "Congestive fever" was once used to describe this |
| 27% | BOWLING | 7 | Sport that is the key to interpreting the answers to 21-, 40- and 56-Across |
| 27% | ULCER | 5 | Stomach ailment once believed to be caused by stress |