| 100% | RNA | 3 | Genetic material whose first letter stands for "ribo" (Abbr.) |
| 92% | RNA | 3 | Genetic material whose first letter stands for "ribo" |
| 60% | DEA | 3 | Agency whose first letter stands for Drug |
| 60% | VCHIP | 5 | Technology whose first letter stands for "violence" |
| 59% | BLT | 3 | Sandwich whose first letter stands for 11-Down |
| 59% | SMS | 3 | Digital protocol whose first letter stands for short |
| 59% | XPLANE | 6 | Research aircraft whose first letter stands for "experimental" |
| 59% | UBOAT | 5 | Naval craft whose first letter stands for untersee |
| 56% | GEICO | 5 | Insurance company whose first letter stands for "government," though it's a private company |
| 52% | HRH | 3 | Regnal abbreviation whose first letter can stand for two different words |
| 52% | XFL | 3 | Gridiron org. whose first letter did not, in fact, stand for "extreme" |
| 48% | UBOAT | 5 | Its first letter stands for "untersee" |
| 48% | IPA | 3 | Its first letter stands for "India" |
| 48% | DDT | 3 | Its first letter stands for "dichloro-" |
| 47% | LBS | 3 | Units whose name's first letter stands for an ancient-Roman unit of measurement |
| 46% | PCOS | 4 | Common condition whose first two letters stand for "polycystic" |
| 45% | HMART | 5 | Supermarket chain whose name's first letter stands for the Korean phrase han ah reum |
| 43% | OCR | 3 | Tech whose last letter stands for "recognition" |
| 43% | ORALB | 5 | Brand whose last letter stands for "brush" |
| 43% | ATM | 3 | Abbreviation whose middle letter stands for "teller" |
| 43% | LSAT | 4 | Exam whose first initial stands for "Law" |
| 42% | APR | 3 | Month whose first day is known for pranks: Abbr. |
| 41% | CMYK | 4 | Color model whose last letter stands for "key" |
| 41% | JPEG | 4 | Tech acronym whose last letter stands for group |
| 41% | ORALB | 5 | Brand name whose last letter stands for "brush" |
| 41% | NASDAQ | 6 | Exchange name whose last letter stands for Quotations |
| 41% | AHS | 3 | FX show whose middle letter stands for "horror" |
| 41% | XXXX | 4 | Its first letter doesn't stand for "oil" |
| 41% | QTIP | 4 | A Tribe Called Quest member whose name's first letter stands for his home borough |
| 41% | TCM | 3 | Cable channel whose first initial stands for its founder |