| 100% | DNAS | 4 | Genetic materials that may prove (or not) that many guys are dads after all |
| 46% | RNA | 3 | Genetic material that may be "transfer" or "messenger": Abbr. |
| 37% | LORE | 4 | Stories that may or may not be true |
| 37% | ITS | 3 | Word that may or may not be apostrophized |
| 37% | DNA | 3 | Genetic material that can be extracted from hair or saliva: Abbr. |
| 37% | WERE | 4 | Word that may or may not be a contraction |
| 37% | ILL | 3 | Word that may or may not be a contraction |
| 36% | TINORE | 6 | Raw material that might be made into bronze or pewter |
| 35% | UFOS | 4 | Vehicles that may or may not be stored in Area 51: Abbr. |
| 34% | DANQUAYLE | 9 | Veep who said "We are ready for any unforeseen event that may or may not occur" |
| 32% | CAGEFREEEGG | 11 | It may not be all that it's cracked up to be |
| 32% | DENIM | 5 | Material that may be acid-washed |
| 31% | GOOD | 4 | With 65-Across, comment that might be heard after the start of 17-, 28-, 45- or 59-Across |
| 31% | DATASET | 7 | Material that may be processed into tables? |
| 31% | TAR | 3 | Material that may be used to repair potholes |
| 31% | ORE | 3 | Material that may be carried in a cart |
| 31% | STEEL | 5 | Material that might be processed in a bloomery |
| 31% | CLINGY | 6 | Material that induces static or is too tight |
| 31% | WIRE | 4 | Fence material that may be barbed |
| 31% | AFEW | 4 | Not all that many |
| 30% | DNA | 3 | Genetic substance that may be entered into evidence: Abbr. |
| 30% | CHILI | 5 | Dish that may or may not contain beans |
| 30% | EVIDENCE | 8 | Fact or information that prove someone is guilty |
| 30% | EVIDENCE | 8 | Facts or information that prove someone is guilty |
| 30% | LACE | 4 | Frilly material that may be used in 5a |
| 30% | DNA | 3 | Cell material that may be courtroom evidence: Abbr. |
| 30% | DNA | 3 | Genetic substance that may be used as evidence in court: Abbr. |
| 30% | ITS | 3 | Word that may or may not contain an apostrophe |
| 30% | SLAW | 4 | Side dish that may or may not include mayo |
| 30% | LEGOBRICK | 9 | Construction material that might be given as a gift |