| 100% | GRISSOM | 7 | Gil ___, original lead role on "CSI" |
| 58% | SYD | 3 | Lead role on "Providence" |
| 58% | ISSA | 4 | Lead role on “Insecure” |
| 57% | TONY | 4 | Lead role on 23-Across |
| 57% | LIZ | 3 | Lead role on "30 Rock" |
| 56% | SYD | 3 | Lead role on TV's "Providence" |
| 56% | LESLIE | 6 | Lead role on "Parks and Recreation" |
| 55% | LIZ | 3 | Lead role on TV's "30 Rock" |
| 55% | ELLIE | 5 | Leading role on "The Last of Us" |
| 55% | MATT | 4 | ___ Dillon, lead role on "Gunsmoke" |
| 55% | SELINA | 6 | ___ Meyer, lead role on "Veep" |
| 54% | ROBPETRIE | 9 | Lead role on “The Dick Van Dyke Show” |
| 53% | YATES | 5 | Rowdy ___, lead role on TV's "Rawhide" |
| 51% | HARTNELL | 8 | William, first to play lead role on Doctor Who |
| 51% | DOVECAMERON | 11 | She played both lead roles on "Liv & Maddie" |
| 51% | FRED | 4 | Lead role in "Miracle on 34th Street" |
| 48% | BOBODENKIRK | 11 | "Breaking Bad" actor who plays the lead role on 33-Across: 2 wds. |
| 47% | STEVENVANZANDT | 14 | E Street Band guitarist who had a leading role on "The Sopranos": 3 wds. |
| 46% | DEADBODY | 8 | Nonspeaking role on "CSI" |
| 44% | PETERSEN | 8 | William who played Gil on CSI |
| 44% | TOPOL | 5 | Best Actor in a Leading Role Oscar nominee for Fiddler on the Roof |
| 43% | CLAIRE | 6 | Lead female role on Netflix's "House of Cards" |
| 43% | VOSK | 4 | Jessica who played the lead role, Elphaba, in "Wicked" on Broadway in 2018-19 |
| 42% | FINNEY | 6 | Albert —, Best Actor in a Leading Role Oscar nominee for Murder on the Orient Express |
| 42% | ALECGUINNESS | 12 | Best Actor in a Leading Role Oscar winner for The Bridge on the River Kwai |
| 42% | TONE | 4 | Franchot —, a Best Actor in a Leading Role Oscar nominee for Mutiny on the Bounty |
| 41% | GUINNESS | 8 | Alec —, Best Actor in a Leading Role Oscar winner for The Bridge on the River Kwai |
| 41% | GUINNESS | 8 | Alec —, Best Actor in a Leading Role Oscar-winner for The Bridge on the River Kwai |
| 40% | MAINPART | 8 | Lead role |