| 100% | DANASCULLY | 10 | Gillian Anderson's skeptical FBI investigator in 43-Across: 2 wds. |
| 62% | FOXMULDER | 9 | David Duchovny's truth-seeking FBI investigator in 43-Across: 2 wds. |
| 41% | DANASCULLY | 10 | Gillian Anderson's 52-Across role (2 wds.) |
| 41% | THEXFILES | 9 | TV series in which Gillian Anderson played FBI agent Dana Scully: 2 wds., hyph. |
| 41% | THEXFILES | 9 | Fox show featuring David Duchovny and Gillian Anderson as FBI agents: 2 wds. |
| 37% | PETERDINKLAGE | 13 | Actor who plays Tyrion Lannister in 43-Across (2 wds.) |
| 35% | BRYANCRANSTON | 13 | "Trumbo" Best Actor Oscar nominee who voices Chief in 43-Across (2 wds.) |
| 35% | VALKILMER | 9 | "The Doors" actor who played the title hero in 43-Across (2 wds.) |
| 35% | JIMCARREY | 9 | "Dumb and Dumber" actor who played The Riddler in 43-Across (2 wds.) |
| 34% | JOHNOLIVER | 10 | Comedian and late-night host who voices Steve the porcupine in 43-Across (2 wds.) |
| 34% | CHEVYCHASE | 10 | Former "Saturday Night Live" regular who plays golfer Ty Webb in 43-Across (2 wds.) |
| 34% | SEXEDUCATION | 12 | Netflix show on which Gillian Anderson played a therapist: 2 wds. |
| 33% | KENANTHOMPSON | 13 | Comedian and "Saturday Night Live" cast member who voices Gus the beaver in 43-Across (2 wds.) |
| 33% | MIKEHAMMER | 10 | Private investigator created by Mickey Spillane played by 43-Across in the 1980s and 1990s (2 wds.) |
| 32% | MOBYDICK | 8 | 2011 miniseries about a whale hunt in which Gillian Anderson (birthday today) played Captain Ahab's wife: 2 wds. |
| 32% | TRIPLECROWN | 11 | Baseball honor earned by 43-Across in 1966 (2 wds.) |
| 32% | THETRESPASSER | 13 | 2016 novel that's the sixth volume in 43-Across's Dublin Murder Squad mystery series (2 wds.) |
| 32% | THETRESPASSER | 13 | 2016 novel that's the sixth volume in 43-Across's "Dublin Murder Squad" mystery series (2 wds.) |
| 32% | PRINCESSPEACH | 13 | Royal damsel in distress in 43-Across (2 wds.) |
| 31% | SUSANSARANDON | 13 | 18-Across and 43-Across actress who plays Carla's mother in "A Bad Moms Christmas" (2 wds.) |
| 30% | SIDNEYPOITIER | 13 | Oscar-winning actor who played 43-Across in a 1997 TV film (2 wds.) |
| 30% | MORGANFREEMAN | 13 | Oscar-winning actor who played 43-Across in the 2009 film "Invictus" (2 wds.) |
| 30% | DUSTINHOFFMAN | 13 | Actor who played 43-Across in the movie "All the President's Men": 2 wds. |
| 30% | ELIEWIESEL | 10 | "Night" memoirist and political activist who won the Nobel 43-Across in 1986 (2 wds.) |
| 30% | ONME | 4 | See 43-Across: 2 wds. |
| 30% | IRON | 4 | Metal in 43 Across |
| 30% | TRUSTNOONE | 10 | "Be suspicious" catchphrase in 43-Across: 3 wds. |
| 30% | JENNIFERBRADY | 13 | American tennis player who was the runner-up to 43-Across in the Women's Singles finals at the Australian Open in 2021 (2 wds.) |
| 29% | NELSONMANDELA | 13 | "Long Walk to Freedom" memoirist and political leader who won the Nobel 43-Across in 1993 (2 wds.) |
| 29% | MICHAELMOORER | 13 | Boxer who lost to 43-Across in the 1994 bout billed as "One for the Ages" (2 wds.) |