| 100% | SAAB | 4 | GM division from 2000 to 2010 |
| 43% | CSI | 3 | CBS procedural that aired from 2000 to 2015 |
| 43% | CSI | 3 | CBS procedural drama that ran from 2000 to 2015 |
| 43% | CSI | 3 | CBS crime drama that ran from 2000 to 2015 |
| 43% | AOSCOTT | 7 | New York Times film critic from 2000 to 2023 |
| 41% | BYRD | 4 | Senator from 1959 to 2010 |
| 40% | AVENGERS | 8 | LA's Arena Football League team that lasted from 2000 to 2009 |
| 40% | FORMAT | 6 | "All sports" or "hits from 2000 to today," for a radio station |
| 38% | TBS | 3 | Airer of “Conan” from 2010 to 2021 |
| 38% | XXXXXXXXXXXXXXX | 15 | Governor of Hawaii from 2010 to 2014 |
| 37% | SPINSOFF | 8 | Converts from a division to a separate company |
| 37% | CONAN | 5 | Late-night talk show from 2010 to 2021 |
| 36% | WHOLETTHEDOGSOUT | 16 | Hit song from 2000 ... and a hint to 10 symmetrically arranged Across answers |
| 36% | CASE | 4 | --> from 2003 to 2010 |
| 34% | HEAT | 4 | Miami ___, NBA team for which LeBron James played from 2010 to 2014 |
| 33% | REDPLANET | 9 | Val Kilmer's sci-fi thriller film from 2000 about an interplanetary mission to Mars: 2 wds. |
| 32% | ONEDIRECTION | 12 | Group that Zayn Malik was a part of from 2010 to 2015: 2 wds. |
| 32% | MERCEDES | 8 | ___ GP Petronas F1 Team, constructor for whom Michael Schumacher drove from 2010 to 2012 |
| 32% | ASTRID | 6 | Hiccup and ___, iconic couple from the 2010 animated film "How To Train Your Dragon" |
| 32% | MISSIONTO | 9 | "___ Mars," American sci-fi film from 2000 about a manned exploration mission to Mars that goes wrong: 2 wds. |
| 32% | PRI | 3 | Mex. ruling party from 1929 to 2000 |
| 32% | CHICKENRUN | 10 | 2000 stop-motion movie about a rooster trying to help hens escape from a farm: 2 wds. |
| 32% | KELLYOSBOURNE | 13 | Daughter of Ozzy and Sharon who cohosted 54-Across from 2010 to 2015: 2 wds. |
| 31% | CIVICNA | 7 | Home of the Pittsburgh Penguins from 1967 to 2010 |
| 31% | LORENAOCHOA | 11 | Mexican golfer who was #1 in the LPGA from April 2007 to May 2010: 2 wds. |
| 31% | OLDS | 4 | Bygone GM division |
| 31% | OLDS | 4 | Former GM division |
| 31% | OLDS | 4 | Erstwhile GM division |
| 30% | COMINGBACKTO | 12 | "___ Life," Pink Floyd's song from "The Division Bell" which was credited solely to David Gilmour: 3 wds. |
| 30% | CHEVROLET | 9 | GM division, makes the Camaro and Silverado |