| 100% | NOELGALLAGHER | 13 | Guitarist who played with his brother Liam on the Oasis hit "Wonderwall": 2 wds. |
| 60% | EDDIEVANHALEN | 13 | Guitarist who played with his brother Alex on their namesake band's hit "Jump": 3 wds. |
| 58% | ANGUS | 5 | With 33-Across, guitarist who played with his brother Malcolm on the AC/DC hit "Highway to Hell" |
| 42% | TIKIBARBER | 10 | NFL running back who played alongside his twin brother, Ronde, at the University of Virginia and on three Pro Bowl teams: 2 wds. |
| 41% | ERICCLAPTON | 11 | "Layla" guitarist who shares his first name with the prince in "The Little Mermaid": 2 wds. |
| 40% | EDSHEERAN | 9 | Singer who collaborated with Beyoncé on the 2017 #1 hit "Perfect Duet": 2 wds. |
| 40% | SEANPAUL | 8 | Rapper who collaborated with Beyoncé on the 2003 #1 hit "Baby Boy": 2 wds. |
| 40% | EMILYMEADE | 10 | Actress who plays Aimee, Jill's high school friend on the hit TV series "The Leftovers": 2 wds. |
| 40% | ORVILLEWRIGHT | 13 | Aviation pioneer who, with his brother Wilbur, built the first piloted, engine-powered plane: 2 wds. |
| 40% | ORVILLEWRIGHT | 13 | Inventor who, along with his elder brother, developed the first the airplane: 2 wds |
| 40% | PAULHAMM | 8 | Gymnast who competed with his twin brother, Morgan, at the 2000 and 2004 Summer Olympics: 2 wds. |
| 40% | BROOKLOPEZ | 10 | NBA center who played alongside his twin brother, Robin, for the Milwaukee Bucks: 2 wds. |
| 39% | KEVINNEALON | 11 | "Weeds" actor who plays Adam's brother Don on "Man With a Plan": 2 wds. |
| 39% | SHIRLEYJONES | 12 | Stepmother of 19-Across who played his mother on "The Partridge Family": 2 wds. |
| 39% | LARRYHAGMAN | 11 | Actor who plays the oldest Ewing brother on 32-Down (2 wds.) |
| 38% | TOBYKEITH | 9 | Singer who duetted with Willie Nelson on the 2003 #1 country hit "Beer for My Horses": 2 wds. |
| 38% | DERRICKTHOMAS | 13 | NFL pass rusher who played his entire career with the Kansas City Chiefs and is considered one of the greatest of all time: 2 wds. |
| 37% | KYLETURLEY | 10 | Former NFL lineman who played for the St. Louis Rams who went on to form a self-titled band and establish his own record label: 2 wds. |
| 37% | JIMMIEWALKER | 12 | Actor who played J.J. Evans, the character with the catchphrase "Dy-no-mite!" on the 1970s sitcom "Good Times": 2 wds. |
| 37% | ALEXKARRAS | 10 | Actor who played the adoptive father on "Webster": 2 wds. |
| 37% | EMMANUELLEWIS | 13 | Actor who played the title character on "Webster": 2 wds. |
| 37% | POLLYHOLLIDAY | 13 | Actress who played waitress Flo on the sitcom "Alice": 2 wds. |
| 37% | COURTENEYCOX | 12 | Actress who played the chef Monica Geller on "Friends": 2 wds. |
| 36% | GINARODRIGUEZ | 13 | Actress who plays the title role on 15-Across: 2 wds. |
| 36% | ALLISONJANNEY | 13 | Actress who plays Bonnie, the title mom on "Mom": 2 wds. |
| 36% | JOHNELWAY | 9 | Hall of Fame quarterback who played his whole career with the Broncos (1983-1998): 2 wds. |
| 36% | TERRYBRADSHAW | 13 | Hall of Fame quarterback who played his whole career with the Steelers (1970-1983): 2 wds. |
| 36% | BARTSTARR | 9 | Hall of Fame quarterback who played his whole career with the Packers (1956-1971): 2 wds. |
| 36% | SPENCERTRACY | 12 | Actor who played the lawyer based on Clarence Darrow in 32-Across: 2 wds. |
| 36% | BARBARABAIN | 11 | Actress who played Cinnamon Carter on the 1966-1973 series "Mission: Impossible": 2 wds. |