| 100% | OPENED | 6 | Had the first act |
| 72% | OPEN | 4 | Be the first act |
| 72% | OPENS | 5 | Is the first act |
| 66% | OPEN | 4 | Serve as the first act |
| 65% | PREMIERED | 9 | Had the first showing (of), as a film |
| 65% | DICTIONARY | 10 | It has the first & last word |
| 64% | OPENS | 5 | Is the first act of a concert |
| 64% | WORLDSFAIR | 10 | London had the first one in 1851 |
| 63% | BREAKFASTED | 11 | Had the day's first meal |
| 62% | TANTRUM | 7 | The first worker has strange outburst |
| 62% | NAPLES | 6 | City in Italy that had the first-known pizzeria |
| 61% | TEN | 3 | The first number to have two digits |
| 61% | ZOO | 3 | Philadelphia had the first one in the U.S. (1874) |
| 61% | EMERALDS | 8 | First act of the ballet "Jewels," by George |
| 58% | NWA | 3 | Group that had the first hardcore rap album to reach #1 on Billboard |
| 57% | IOWA | 4 | State where the first presidential caucuses have traditionally occurred |
| 56% | ABBA | 4 | Swedish pop band that has the first letter of each member on its name |
| 56% | THOUSAND | 8 | This is the first number to have the letter "A" |
| 56% | TORRE | 5 | Manager who preceded Girardi (and has the same first name) |
| 56% | BEASTIE | 7 | The __ Boys, supporting act on first Madonna tour |
| 56% | BTS | 3 | First Korean act to perform at the Grammys |
| 55% | GTOS | 4 | Classic cars that were the first to have Ram Air engines |
| 54% | ALEC | 4 | Alphabetically first of the acting Baldwin brothers |
| 54% | OBAMA | 5 | The first bill he signed into law was the Lilly Ledbetter Fair Pay Act |
| 54% | GEHRIG | 6 | Yankee who was the first major-leaguer to have his number retired |
| 54% | HAYES | 5 | First president to have a telephone in the White House |
| 53% | LUISE | 5 | Rainer who was the first person to win two Academy Awards for acting |
| 53% | MADAMSPEAKER | 12 | *Nancy Pelosi was the first person ever to have this title in Congress |
| 53% | ORR | 3 | He was the first hockey player to have 100 assists in one season |
| 53% | JACKSON | 7 | First president to have running water in the White House (1833) |