| 100% | RON | 3 | Harry Potter character whose middle name is Bilius |
| 58% | BART | 4 | TV character whose middle name is JoJo |
| 58% | RICHIERICH | 10 | Comic book character whose middle name is $ |
| 57% | JAMESKIRK | 9 | TV/movie lead character whose middle name is Tiberius |
| 57% | KIRK | 4 | Well known TV character whose middle name is Tiberius |
| 50% | DIAGONALLEY | 11 | Harry Potter thoroughfare whose name is a play on an adverb |
| 46% | ELTONJOHN | 9 | Singer whose middle name is Hercules |
| 46% | ELTON | 5 | John whose middle name is Hercules |
| 46% | KIRK | 4 | Captain whose middle name is Tiberius |
| 46% | MOZART | 6 | Composer whose middle name is Amadeus |
| 46% | ONASSIS | 7 | Magnate whose middle name was Socrates |
| 46% | GEISEL | 6 | Theodor whose middle name was Seuss |
| 46% | TAFT | 4 | President whose middle name was Howard |
| 46% | MOZART | 6 | Austrian composer whose middle name is Amadeus |
| 46% | KHLOE | 5 | Kardashian sister whose middle name is Alexandra |
| 46% | GROBAN | 6 | Singer Josh whose middle name is Winslow |
| 46% | BART | 4 | Cartoon boy whose middle name is JoJo |
| 46% | UMA | 3 | Actress Thurman whose middle name is Karuna |
| 46% | REMBRANDT | 9 | Dutch artist whose middle name was Harmenszoon |
| 46% | EDISON | 6 | Famous inventor whose middle name was Alva |
| 45% | OPRAH | 5 | Celebrity whose middle name is Gail, appropriately enough |
| 45% | HUGHGRANT | 9 | British actor whose middle names are John Mungo |
| 45% | MICHAEL | 7 | ___ J. Fox (actor whose middle name is actually Andrew) |
| 44% | DRACO | 5 | Harry Potter nemesis Malfoy whose first name is also a 49-Across |
| 42% | MAGOO | 5 | Cartoon character whose first name is Quincy |
| 42% | MRDEEDS | 7 | Film character whose first name is Longfellow |
| 42% | MICAWBER | 8 | Dickens character whose first name is Wilkins |
| 42% | DRNO | 4 | Movie character whose first name is Julius |
| 42% | MRMOTO | 6 | Fictional character whose first name is Kentaro |
| 42% | REN | 3 | Cartoon character whose last name is Höek |