| 100% | THEWIRE | 7 | HBO drama set in Baltimore (2 wds.) |
| 67% | GREYSANATOMY | 12 | ABC medical drama set in Seattle: 2 wds. |
| 66% | THELEFTOVERS | 12 | New HBO drama set after the Rapture: 2 wds. |
| 66% | LALAW | 5 | 1980s-1990s legal drama set in Southern California: 2 wds. |
| 66% | LALAW | 5 | 1986-1994 legal drama set in Southern California: 2 wds. |
| 66% | MIAMIVICE | 9 | Stylish '80s police drama set in Florida: 2 wds. |
| 63% | INTREATMENT | 11 | HBO drama in which Dianne Wiest played a psychotherapist: 2 wds. |
| 63% | THEPITT | 7 | HBO Max medical drama starring Noah Wyle and set in Pennsylvania: 2 wds. |
| 62% | THEWIRE | 7 | HBO crime drama series set in Baltimore |
| 61% | NEWAMSTERDAM | 12 | NBC medical drama set in one of the oldest public hospitals in the US: 2 wds. |
| 61% | BIGLOVE | 7 | HBO drama set in Utah |
| 61% | GREYSANATOMY | 12 | Medical drama set in Seattle with a 2011 same-sex wedding between Callie and Arizona: 2 wds. |
| 60% | THENEWSROOM | 11 | 2012-2014 HBO drama in which Olivia Munn played an economist: 2 wds. |
| 60% | THEOC | 5 | 2000s teen drama set in Newport Beach (2 wds.) |
| 60% | CHICAGOFIRE | 11 | TV drama set in the Prairie State (2 wds.) |
| 60% | HAWAIIFIVEO | 11 | TV drama set in the Aloha State (2 wds.) |
| 59% | THEOC | 5 | 2000s teen drama set in Newport Beach, California (2 wds.) |
| 59% | TREME | 5 | HBO drama set in post-Katrina New Orleans |
| 58% | GREYSANATOMY | 12 | Ellen Pompeo drama set in Seattle (2 wds.) |
| 58% | CSIMIAMI | 8 | Long-running police drama set in Florida starring David Caruso (2 wds.) |
| 57% | BIGLOVE | 7 | Erstwhile HBO drama set in suburban Salt Lake City |
| 57% | MIAMIVICE | 9 | 1980s police drama set in Florida starring 15-Across and 33-Across (2 wds.) |
| 56% | ALLYMCBEAL | 10 | Former FOX legal drama set in Boston (2 wds.) |
| 56% | STELSEWHERE | 11 | Former NBC medical drama set in Boston (2 wds.) |
| 56% | NURSEJACKIE | 11 | Showtime comedy-drama set in a hospital that ended this summer: 2 wds. |
| 54% | THEWIRE | 7 | Hit HBO series set in Baltimore |
| 54% | NCISNEWORLEANS | 14 | TV drama set in the Pelican State (3 wds.) |
| 54% | ITOO | 4 | "Am ___ set in my ways?": 2 wds. |
| 51% | HAWAIIFIVEO | 11 | Police drama set in the Aloha State that featured Carol Burnett in a recurring role as Steve McGarrett's aunt (2 wds.) |
| 51% | THENEWSROOM | 11 | HBO drama about a fictional cable channel's staff: 2 wds. |