| 100% | CSINY | 5 | Hit TV series featuring 54-Across |
| 58% | ALLY | 4 | "___ McBeal" (hit TV series featuring singer Vonda Shepard) |
| 53% | STARTREK | 8 | TV series featuring Picard, Discovery |
| 52% | CSINY | 5 | Hit TV series starring Gary Sinise |
| 52% | CSI | 3 | Hit TV series with three spinoffs |
| 51% | XENA | 4 | TV series featuring the war god Ares |
| 51% | CSI | 3 | Hit TV series set in Las Vegas |
| 51% | FAMILYGUY | 9 | Animated TV series featuring the voices of Seth MacFarlane and 43-Across (2 wds.) |
| 51% | FAMILYGUY | 9 | Animated TV series featuring the voices of Seth MacFarlane and 42-Across (2 wds.) |
| 50% | LOKI | 4 | TV series featuring the Norse god of mischief |
| 50% | UGLYBETTY | 9 | Hit TV series based on a Colombian telenovela |
| 50% | GLEE | 4 | Musical TV series featuring Jane Lynch |
| 50% | TREK | 4 | "Star ___" (classic TV series featuring Klingons) |
| 50% | ABBEY | 5 | "Downton ___," TV series featuring the Crawleys |
| 50% | NINJAGO | 7 | Lego TV series featuring Lloyd Garmadon |
| 50% | MONEY | 5 | "___ Heist," TV series featuring The Professor |
| 50% | RUSSIANDOLL | 11 | Netflix TV series whose 2022 season features 13-Across: 2 wds. |
| 49% | DOCTORWHO | 9 | TV series featuring a robotic dog named K-9 |
| 49% | GLEE | 4 | TV series featuring the high-school choir New Directions |
| 49% | THEWIRE | 7 | Hit TV series by David Simon set in Baltimore |
| 49% | SESAME | 6 | __ Street, children's TV series featuring Elmo |
| 49% | SCHITTSCREEK | 12 | 2015-2020 hit TV series costarring 13-Across as Alexis Rose: 2 wds. |
| 49% | ATLANTA | 7 | TV series featuring rapper Paper Boi and his cousin Earn |
| 48% | KENT | 4 | Clark ___, of the hit TV series "Lois & Clark" |
| 48% | EPPS | 4 | Actor Omar ___, from the hit TV series "House" |
| 47% | WHITECOLLAR | 11 | Recent Matt Bomer TV series that featured 34-Across as June Ellington: 2 wds. |
| 47% | THEXFILES | 9 | Paranormal TV series featuring the characters 15-Across, 21-Across, and 41-Across that debuted in 1993 (2 wds.) |
| 47% | GLEE | 4 | Former TV series featuring the high-school choir New Directions |
| 46% | STAR | 4 | With 32-Across, 1966-1969 sci-fi TV series featuring 18-Across |
| 45% | GENIUS | 6 | Nat Geo TV series featuring stories about Albert Einstein and Pablo Picasso |