| 100% | FRODO | 5 | Hobbit whose best friend is Sam |
| 61% | KEN | 3 | Doll whose best friend is Allan |
| 60% | NAPOLEON | 8 | Dynamite character whose best friend is Pedro |
| 60% | DORA | 4 | Cartoon explorer whose best friend is Boots |
| 60% | DORA | 4 | Cartoon girl whose best friend is Boots |
| 60% | DORATHEEXPLORER | 15 | Animated TV character whose best friend is Boots |
| 60% | HEIDI | 5 | Literary heroine whose best friend is a goatherd |
| 60% | YOGI | 4 | Animated bear whose best friend is Boo-Boo |
| 58% | DORA | 4 | Cartoon explorer whose best friend is a monkey named Boots |
| 57% | SPONGEBOB | 9 | First name of the cartoon character whose best friend is Patrick Star |
| 55% | CHUCKIEFINSTER | 14 | Nickelodeon cartoon character with red hair whose best friend is Tommy Pickles (2 wds.) |
| 54% | ELMO | 4 | Red Muppet on "Sesame Street" whose best friend is a pink fairy named Abby Cadabby |
| 54% | PRINCESSMERIDA | 14 | Disney cartoon character with red hair whose best friend is a horse named Angus (2 wds.) |
| 50% | GEORGE | 6 | With 35-Across, Hanna-Barbera cartoon character with red hair whose best friend is a supercomputer named R.U.D.I. |
| 43% | HIS | 3 | "A boy's best friend is ___ mother" ("Psycho" quote) |
| 41% | SQUAD | 5 | "___ goals!" ("Our friends are the best!") |
| 41% | DOG | 3 | "Man's best friend"; Snoopy was one |
| 41% | TSO | 3 | General whose good name has been battered? |
| 39% | CHANDLER | 8 | Friends character whose surname is a cherry |
| 39% | DANTE | 5 | Poet whose best-known work is 14,233 lines long |
| 38% | OILMAN | 6 | One whose success is well-earned? |
| 38% | OILTYCOON | 9 | One whose success is well-earned? |
| 38% | TAILORS | 7 | Ones whose jobs are good fits? |
| 38% | HELEN | 5 | With 25 Across, author whose best-known character is named Jones |
| 38% | HENRY | 5 | With 25 Across, author whose best-known character is named Jones |
| 38% | ALAN | 4 | Barbie's boyfriend's best friend who was introduced in 1964 |
| 38% | ZAPPA | 5 | Rocker whose best-selling album was the punnily titled "Sheik Yerbouti" |
| 38% | AMI | 3 | Bon ___ (cleanser whose name is French for "good friend") |
| 38% | BILBO | 5 | "The Hobbit" hero whose cousin is Frodo |
| 37% | LISTENS | 7 | Is a good friend, in a way |