| 100% | ANDES | 5 | Home of the two deepest canyons in the Americas (each 11,500+ feet) |
| 47% | PERU | 4 | Home of the 11,000-foot-deep Cotahuasi Canyon |
| 46% | PERU | 4 | Home of the Cotahuasi Canyon, which is more than two miles deep |
| 44% | SAUDIARABIA | 11 | Home of the two holiest cities in Islam |
| 44% | TORONTO | 7 | Home of the largest street fair in North America |
| 42% | LIMA | 4 | Home of the oldest university in the continental Americas |
| 40% | LIMA | 4 | Home of the oldest university in the Americas |
| 40% | LIMAPERU | 8 | Home of the oldest continuously functioning university in the Americas |
| 40% | LIMA | 4 | Home of the oldest university in the Americas (founded 1551) |
| 38% | PGATOUR | 7 | Home of some of the best drivers in No. America |
| 38% | STORE | 5 | One of 500+ in the Mall of America |
| 37% | TEXASHOLDEM | 11 | Variant of the card game poker in which each player starts with two cards only |
| 36% | KAN | 3 | Home of the largest grain elevator in the world: Abbr. |
| 36% | UTAH | 4 | Home of the largest saltwater lake in the Western Hemisphere |
| 36% | HAWAII | 6 | Home of the only royal residence in the United States |
| 36% | UTAH | 4 | Home of the historic Desolation Canyon |
| 36% | GENERAL | 7 | Word in the names of two of the top 10 Fortune 500 companies |
| 35% | WAS | 3 | Word seen 11 times in the opening line of "A Tale of Two Cities" |
| 35% | FRANCE | 6 | Home of the first Winter Olympics in 1924 |
| 35% | MILAN | 5 | Home of the largest soccer stadium in Italy |
| 35% | FRANCE | 6 | Home of the most Literature Nobelists in history |
| 35% | ARA | 3 | 11 seasons known as the "Era of ___" in which Notre Dame won two national titles |
| 35% | GRAND | 5 | The ___ Canyon, located in Arizona, that is one of America's natural wonders |
| 35% | SYRIA | 5 | Modern-day home of the oldest discovered library in the world |
| 34% | TDS | 3 | Tom Brady and Matt Ryan each threw two of these in the 2017 Super Bowl: Abbr. |
| 34% | BIRDS | 5 | There are two, as the expression goes, in each of 16- and 55-Across |
| 34% | TWIN | 4 | One of the two main characters in "The Parent Trap" |
| 34% | LSD | 3 | One of the two drugs involved in candyflipping |
| 34% | KAUAI | 5 | Hawaiian island that is home to Waimea Canyon which was used in the filming of "Jurassic Park" |
| 34% | SPRINGBREAK | 11 | Popular vacation time ... and an explanation of what's straddling the two words in each theme answer? |