| 100% | BENSTILLER | 10 | Host of a 1990s sketch comedy show who starred in and wrote both "Zoolander" movies (2 wds.) |
| 46% | ORLANDOBLOOM | 12 | Actor who starred in both the "Pirates of the Caribbean" and "Lord of the Rings" movie franchises: 2 wds. |
| 44% | AMYSCHUMER | 10 | Sketch comedy performer who wrote and stars in 41-Across: 2 wds. |
| 42% | ROSIEODONNELL | 13 | Host of a self-titled talk show who hosted the 1999 and 2000 Grammy ceremonies: 2 wds. |
| 42% | ELLENDEGENERES | 14 | Talk show host and star of a 1990s ABC sitcom, whose title was her first name: 2 wds. |
| 42% | GEORGECLOONEY | 13 | Actor who starred in and made his directorial debut with 2002's "Confessions of a Dangerous Mind": 2 wds. |
| 41% | HARRISONFORD | 12 | Actor who starred in both the "Star Wars" and "Indiana Jones" movie franchises: 2 wds. |
| 41% | ROSEANNEBARR | 12 | 1990s sitcom star who was the subject of a Comedy Central Roast in 2012: 2 wds. |
| 39% | ROSEANNEBARR | 12 | Title star of a 1990s sitcom who was the honoree of a 2012 Comedy Central roast: 2 wds. |
| 38% | LINDSAYLOHAN | 12 | Actress who starred as both the twins in 29a, a 1998 hit based on the novel "Lottie and Lisa": 2 wds. |
| 38% | SATURDAYNIGHT | 13 | "____ Live," a sketch comedy show on NBC, which 40a hosted in 2016: 2 wds. |
| 37% | INLIVINGCOLOR | 13 | 1990s sketch comedy show featuring 45-Across as a member of The Fly Girls dance troupe (3 wds.) |
| 37% | HARRISONFORD | 12 | Actor who starred in the 1993 movie version of "The Fugitive": 2 wds. |
| 37% | ANGELINAJOLIE | 13 | Actress who stars in, wrote, directed, and coproduced 16-Across: 2 wds. |
| 37% | INGRIDBERGMAN | 13 | Swedish-born actress who starred in the 1940s movies "Gaslight" and "Casablanca": 2 wds. |
| 36% | OZZYOSBOURNE | 12 | Heavy metal singer who starred in a 2002-2005 MTV reality show about his family: 2 wds. |
| 36% | FESSPARKER | 10 | Actor who starred in the title roles of TV's "Davy Crockett" and "Daniel Boone": 2 wds. |
| 36% | EDDIEREDMAYNE | 13 | British actor who stars in the new movie "Fantastic Beasts and Where to Find Them": 2 wds. |
| 36% | SCOTTEASTWOOD | 13 | Actor who stars in "The Fate of the Furious", and whose father is Clint Eastwood: 2 wds. |
| 36% | DUSTINHOFFMAN | 13 | "Tootsie" actor who starred in "Death of a Salesman" on Broadway in 1984: 2 wds. |
| 36% | CAMERONDIAZ | 11 | "The Mask" actress who starred in the 2002 movie "Gangs of New York": 2 wds. |
| 36% | GRETAGARBO | 10 | Swedish-born actress who starred in the 1930s movies "Mata Hari" and "Grand Hotel": 2 wds. |
| 36% | GENESIMMONS | 11 | Kiss bassist/singer who starred in an A&E reality show about his family: 2 wds. |
| 36% | WENDELLPIERCE | 13 | "The Wire" actor who starred in "Death of a Salesman" on Broadway in 2022: 2 wds. |
| 35% | STEPHENCOLBERT | 14 | Host of "The Late Show" who was once a correspondent on "The Daily Show": 2 wds. |
| 35% | JOHNOLIVER | 10 | Host of "Last Week Tonight" who was once a correspondent on "The Daily Show": 2 wds. |
| 35% | HUGHOBRIAN | 10 | Actor who starred in the title role of TV's "The Life and Legend of Wyatt Earp": 2 wds. |
| 35% | TERRYBRADSHAW | 13 | A former NFL player who starred in "Failure to Launch" and currently co-hosts Fox NFL Sunday: 2 wds |
| 35% | GEORGELOPEZ | 11 | Comedian who starred in a self-titled sitcom from 2002 to 2007, and another that started in 2016: 2 wds. |
| 35% | TREVORNOAH | 10 | Former host of "The Daily Show" who was born in South Africa in 1984: 2 wds. |