| 100% | SOLO | 4 | How Joshua Slocum sailed around the world starting in 1895, becoming the first person to do so |
| 39% | MANNYPACQUIAO | 13 | Filipino boxer who recently became the first person to hold a world title in four different decades: 2 wds. |
| 37% | STEVE | 5 | Fossett, who was the first person to fly around the world alone, in 1995, covering 20,482.26 miles |
| 36% | MAGELLAN | 8 | First to sail around the world |
| 35% | RICHARDBYRD | 11 | American explorer who in 1929 became the first person to fly over the South Pole: 2 wds. |
| 34% | WILEYPOST | 9 | First person to fly solo around the world (1933) |
| 34% | THENETHERLANDS | 14 | European country that legalized same-sex marriage on April 1, 2001, the first country in the world to do so (2 wds.) |
| 34% | ROALDAMUNDSEN | 13 | Norwegian explorer who in 1911 became the first person to reach the South Pole, one month ahead of 18-Across: 2 wds. |
| 33% | ALTHEAGIBSON | 12 | In 1957, she became the first person of color to win a Wimbledon championship (2 wds.) |
| 33% | XGAMES | 6 | 2013 competition where Mitchie Brusco became the first person to land a 1080 at in the Big Air event |
| 33% | DRAKE | 5 | Francis who was the first Englishman to sail around the world |
| 33% | MARIAHCAREY | 11 | "Fantasy" singer who recently became the first person to top the Billboard Hot 100 in four different decades: 2 wds. |
| 30% | CNN | 3 | Channel started in 1980 that was the first in the world to provide 24-hour news coverage |
| 29% | ABEL | 4 | First person to die in the Bible |
| 29% | GIBB | 4 | Bobbi, who in 1966 became the first woman to run the entire Boston Marathon |
| 29% | JOHNYOUNG | 9 | First person to fly solo around the Moon |
| 29% | WILMA | 5 | Considered the world's fastest woman in the 60s, she became the first American woman to win three golds in a single Olympic Games |
| 29% | ORANGUTANS | 10 | In 2014 Argentina became the first country to recognize these primates' legal rights |
| 29% | ELMO | 4 | He became the first puppet to testify before Congress in 2002 |
| 29% | ERICBANA | 8 | First person to play the Hulk in the 2000s |
| 28% | ROALD | 5 | ___ Amundsen, Norwegian explorer who became the first person to reach the South Pole on 14th December, 1911 |
| 28% | SARAHPALIN | 10 | In 2006, she became the first woman to be elected governor of Alaska: 2 wds. |
| 28% | JESMYNWARD | 10 | In 2017, she became the first woman to win two National Book Awards for fiction |
| 28% | JACOBS | 6 | A. J. ___, author of the best seller "The Know-It-All: One Man's Humble Quest to Become the Smartest Person in the World" |
| 28% | VALENTINA | 9 | ___ Tereshkova, cosmonaut who became the first woman to fly in space in 1964 |
| 28% | ITO | 3 | In 1981, she became the first woman to land a triple-triple jump combination in competition |
| 28% | SHERYL | 6 | I wrote "Lean In" and became the first woman to join Facebook's board of directors |
| 28% | SUSANAMARTINEZ | 14 | In 2010, she became the first woman to be elected governor of New Mexico: 2 wds. |
| 28% | NIKKIHALEY | 10 | In 2010, she became the first woman to be elected governor of South Carolina: 2 wds. |
| 28% | WAYNEGRETZKY | 12 | Hockey legend who was the first since Bobby Orr to tally 100+ assists in a season, and did so 11 times: 2 wds. |