| 100% | THUMBS | 6 | Humans only have two in their hands |
| 46% | GEE | 3 | What this puzzle only has two of; one right here in fact |
| 44% | EYES | 4 | A cyclops only has one of these, while humans have two |
| 44% | THUMBS | 6 | Humans have two of these, one on each hand |
| 40% | FEMALE | 6 | In humans, this sex has two X chromosomes |
| 39% | EPEES | 5 | Weapons that have their electrified tips usually held in place by two small grub screws |
| 39% | DEUCE | 5 | Two in the hand |
| 39% | DEUCE | 5 | Two in a hand |
| 38% | MESAARIZONA | 11 | Only city that has two Spring Training stadiums in the 14-Across (2 wds.) |
| 38% | DEUCE | 5 | Two in one's hand |
| 38% | EDEN | 4 | Place where only two humans ever lived, in the Bible |
| 37% | STRAWS | 6 | A shared milkshake might have two in it |
| 37% | COEDITED | 8 | Having two heads, in a way |
| 37% | BIMODAL | 7 | Having two settings in probability distribution |
| 37% | DUPLE | 5 | Having two beats per measure, in music |
| 36% | HELD | 4 | Had in hands |
| 36% | OWN | 3 | Have in hand |
| 36% | HOLD | 4 | Have in hand |
| 36% | HELD | 4 | Had in hand |
| 36% | HOLDS | 5 | Has in hand |
| 36% | MICS | 4 | What stand-up comedians hold in their hands, for short |
| 36% | ACE | 3 | It has two values in blackjack |
| 36% | SITAR | 5 | It has two bridges in India |
| 36% | YESNO | 5 | Having only two answers |
| 36% | ELI | 3 | ___ Broad, American entrepreneur and philanthropist, who is the only individual to have created two Fortune 500 companies in different industries |
| 35% | NORM | 4 | Having two or three kids in a family, nowadays |
| 35% | MOMMIES | 7 | Heather has two, in a children's book title |
| 35% | CLOCK | 5 | It has two hands, but no arms |
| 35% | CLOCK | 5 | It has a face and two hands |
| 35% | POSSESS | 7 | Have in one's hands |