| 100% | BRUSH | 5 | I am a hairstylist's best friend. I help them comb out stubborn knots. Who am I? |
| 65% | CHALK | 5 | I am a teacher's best friend. I help them write on the blackboard. Who am I? |
| 62% | CAMERA | 6 | I am a photographer's best friend. I help them capture every memory. Who am I? |
| 61% | SAW | 3 | I am a woodworker's best friend, I help them cut through planks of wood. Who am I? |
| 60% | ROD | 3 | I am a fisherman's best friend. I help them pull the fish once it's hooked. Who am I? |
| 54% | KNIFE | 5 | I am a chef's best friend. I help chop veggies for a good stew. Who am I? |
| 40% | EASEL | 5 | I and 28a are an artist's best friends. I hold the canvas. Who am I? |
| 40% | PAINT | 5 | I and 38d are an artist's best friends. I add color to their art. Who am I? |
| 32% | WOODY | 5 | Buzz Lightyear's best friend in "Toy Story" who features in the song "You've Got a Friend in Me" |
| 30% | ACID | 4 | I'm a corrosive liquid that turns litmus paper red. Who am I? |
| 30% | HARE | 4 | I'm a rabbit's "Snow" cousin and the cold never bothered me anyway. Who am I? |
| 29% | WINGMAN | 7 | Person who helps out a single friend at a bar |
| 29% | TUBE | 4 | I'm a slender "testing" container used to make chemical reactions. Who am I? |
| 29% | GOAT | 4 | I'm a "Mountain" animal and the cold never bothered me anyway. Who am I? |
| 29% | DONKEY | 6 | Shrek's best friend in "Shrek" who once said, "Because that's what friends do. They forgive each other" |
| 28% | WHALE | 5 | I'm a "Beluga" Arctic mammal and the cold never bothered me anyway. Who am I? |
| 28% | SEAL | 4 | I'm a "Crabeater" Antarctic animal and the cold never bothered me anyway. Who am I? |
| 28% | BEAR | 4 | I'm a large "Polar" animal and the cold never bothered me anyway. Who am I? |
| 28% | BEAKER | 6 | I'm a lab utensil made of glass and chemists may store 29a in me. Who am I? |
| 28% | RACCOON | 7 | I'm a nocturnal animal with a bandit mask and nimble paws. Who am I? |
| 28% | MAD | 3 | ___ Hatter (Alice's friend who throws a good tea party) |
| 28% | LILO | 4 | ___ Pelekai who's Stitch's best friend in a Disney animated franchise |
| 27% | CMON | 4 | "Be a pal and help me out!" |
| 27% | GIRL | 4 | Diamond's best friend, they say |
| 26% | BERT | 4 | Ernie's best friend on "Sesame Street" for whom Ernie dedicated the song "That's What Friends Are For" |
| 26% | UNCLE | 5 | "Well, I'll be a monkey's ___!" |
| 26% | GIRLS | 5 | "Diamonds Are a ___ Best Friend," song performed by Marilyn Monroe in 1953's "Gentlemen Prefer Blondes" |
| 26% | LEOPARD | 7 | I'm a spotted big cat with speed and strength. I rule the night with my majestic sight. Who am I? |
| 25% | PIGLET | 6 | Winnie-the-Pooh's best friend who once asked, "We'll be friends forever, won't we Pooh?" |
| 25% | DOG | 3 | "Man's best friend"; Snoopy was one |