| 100% | LEVELUP | 7 | Improve a video game character's abilities |
| 56% | FLAVORTEXT | 10 | Words that add depth to a video game character |
| 56% | MARIO | 5 | Video game character with a large mustache |
| 56% | LUIGI | 5 | Video game character in a green hat |
| 56% | SIM | 3 | Video game character speaking a gibberish language |
| 56% | SIM | 3 | Video game character in a virtual city |
| 55% | UPARROW | 7 | Computer key that might make a video game character jump |
| 55% | SONIC | 5 | Video game character in a hit 2020 film |
| 55% | YOSHI | 5 | Video game character with a long, sticky tongue |
| 55% | SONIC | 5 | First video game character to have a balloon in the Macy's Thanksgiving Day Parade |
| 55% | SPAWNPOINT | 10 | Location where a video game character starts (or restarts) a level |
| 55% | SKILLFLOOR | 10 | *Figurative obstacle representing a video gamer's minimum ability to succeed |
| 54% | MARIO | 5 | Video game character who says "It's-a me" |
| 54% | SIM | 3 | Video game character with a plumbob above their head |
| 54% | MARIO | 5 | "The Godfather" author who shares his name with a video game character |
| 54% | SONIC | 5 | Video game character who attacks by rolling into a ball |
| 53% | PACMAN | 6 | Video game character who nibbles up dots in a maze: Hyph. |
| 53% | QBERT | 5 | Video game with a cube-hopping character |
| 52% | BUFFED | 6 | Game character improved with a spell or potion |
| 49% | GOD | 3 | "___ of War," video game series with a character named Ares |
| 49% | MARIO | 5 | First video game character to be honored with a figure in the Hollywood Wax Museum |
| 49% | DRMARIO | 7 | Video game in which a Nintendo character tosses capsules into a medicinal bottle |
| 48% | NPC | 3 | Background character in a video game, briefly |
| 47% | BOSS | 4 | Enemy in a video game's final level |
| 47% | EASY | 4 | Like a video game's first level, often |
| 47% | RALPH | 5 | Wreck-It ___ (2012 movie about a video-game character) |
| 47% | YOSHI | 5 | Video-game character with a prehensile tongue |
| 47% | DONKEYKONG | 10 | Video game with a gorilla that first featured the main character of 43-Across (2 wds.) |
| 46% | MARIO | 5 | Nintendo's iconic video game character |
| 46% | KONG | 4 | Donkey ___, series of video games first released in 1981 and which has a gorilla character |