| 100% | OTIS | 4 | Inventor Boykin who helped develop the pacemaker |
| 51% | COHEN | 5 | Andy who helped develop the "Real Housewives" franchise |
| 44% | GERTRUDEELION | 13 | 1988 American Nobelist in Physiology or Medicine who helped develop the first drug used to fight rejection in organ transplants |
| 43% | JETHRO | 6 | Inventor Tull, who developed the seed drill |
| 39% | EULER | 5 | Leonhard who helped develop calculus |
| 38% | DIRAC | 5 | Nobelist Paul who helped develop quantum mechanics |
| 36% | ROBIN | 5 | Hood who helped the poor |
| 36% | COACH | 5 | Tutor who helps one develop skills |
| 36% | GAMEBREAKER | 11 | One who helps the team win |
| 36% | CHARLIEPARKER | 13 | Saxophonist known as "Yardbird" who helped develop bebop music: 2 wds. |
| 35% | ARIADNE | 7 | Princess who helped Theseus escape the Labyrinth |
| 35% | ASST | 4 | One who helps the Manager, for short |
| 35% | EDISON | 6 | Inventor who saw the light |
| 35% | ELSA | 4 | "Frozen" sister who helped build Olaf the snowman |
| 35% | ALAN | 4 | Turing who helped to crack the Enigma cipher |
| 35% | ARES | 4 | God who helps the Trojans in the "Iliad" |
| 35% | ACCESSORY | 9 | Someone who helps the perpetrator commit a crime |
| 35% | ELSA | 4 | "Frozen" sister who helps build Olaf the snowman |
| 35% | SEXPERT | 7 | One who helps people work out the kinks? |
| 34% | MARYKIES | 8 | Inventor who developed straw weaving technique |
| 34% | RAT | 3 | One who helps break the case |
| 34% | SENATEPAGE | 10 | Teen who helps with the bills |
| 34% | VOCALCOACH | 10 | One who helps you hit just the right note |
| 34% | KELLER | 6 | Helen who helped establish the 46-Down |
| 34% | BABBAGE | 7 | Charles who helped invent the mechanical computer |
| 33% | CLARA | 5 | Heroine who helps the Prince defeat the antagonist in 11a |
| 33% | ARES | 4 | God who helps the Trojans in the "Iliad" |
| 33% | EMILE | 5 | Durkheim who helped found the field of sociology |
| 33% | STOKELY | 7 | Carmichael who helped popularize the phrase black power |
| 33% | ONO | 3 | Yoko who helped establish the John Lennon Scholarships |