| 100% | REFLEX | 6 | Involuntary movement in response to a stimulus |
| 60% | REFLEX | 6 | An involuntary response to a stimulus |
| 55% | REACTION | 8 | Response to a stimulus |
| 53% | REFLEXES | 8 | Automatic body responses to a stimulus |
| 53% | ILLGETIT | 8 | Words in response to a doorbell |
| 52% | AMEN | 4 | Word shouted in response to a pastor |
| 51% | OOF | 3 | Response to a punch, in comics |
| 51% | PLEA | 4 | Response to a charge, in court |
| 51% | FIRE | 4 | Emoji sent in response to a hot outfit pic |
| 51% | REACTION | 8 | Response to a situation, stimulus or treatment |
| 51% | OOF | 3 | Response to a punch in the stomach |
| 51% | OOF | 3 | Response to a punch in the gut |
| 51% | LOL | 3 | Response to a joke in textspeak: Abbr. |
| 50% | LOL | 3 | Response to a joke in a chat room |
| 50% | LOL | 3 | Response to a joke in an I.M. |
| 50% | ITME | 4 | Response to a relatable meme, in internet slang |
| 50% | OOF | 3 | Response to a real kick in the pants |
| 48% | POLO | 4 | Response to "Marco!," in a game |
| 48% | TLDR | 4 | Short response to a long post, in text speak |
| 48% | POLO | 4 | Response to "Marco!" in a pool game |
| 48% | POLO | 4 | Response to "Marco!" in a swimming pool |
| 47% | HOWSOON | 7 | Question in response to "I need this in a hurry" |
| 47% | POLO | 4 | Response to "Marco!" in a swimming pool game |
| 47% | INTHISECONOMY | 13 | Jokey question in response to a statement that may have nothing to do with money |
| 47% | OOF | 3 | Comic strip character's response to a punch in the gut |
| 46% | PABLOPICASSO | 12 | Spanish cubist artist whose antiwar painting "Guernica" was in response to a Nazi bombing: 2 wds. |
| 46% | SOCUTE | 6 | Words spoken in response to seeing a friend's new baby, maybe |
| 45% | ITSOPEN | 7 | "Come on in!" response to a doorbell: 2 wds. |
| 45% | BECAUSEISAIDSO | 14 | Authoritarian response to “Why?” in a parent-child argument |
| 45% | IINSIST | 7 | Response to a polite refusal / (next line) It's spelled out in a Tammy Wynette hit |