| 100% | POUNDSIGN | 9 | It's paired with 3 |
| 73% | AMPERSAND | 9 | It's paired with 7 |
| 69% | GUANINE | 7 | It's paired with cytosine in a DNA strand |
| 64% | HARD | 4 | With 3-Down, it's definitely not light work |
| 63% | MACARONI | 8 | It's often paired with cheese |
| 63% | TONIC | 5 | It's often paired with gin |
| 63% | DINE | 4 | It's often paired with wine? |
| 61% | ANTIGUA | 7 | As an island nation, it's paired with Barbuda |
| 56% | CLOUD | 5 | With 3-Down, it makes the weather overcast |
| 56% | UPFOR | 5 | With 3-Down, available to whoever wants it |
| 55% | REDWINE | 7 | It pairs well with beef |
| 54% | GET | 3 | With 3-Down, "You're not gonna believe it, but ..." |
| 54% | HONOR | 5 | With 3-Down, high marks might get you on it |
| 54% | SWEAT | 5 | With 3-Down, it increases in activity during a workout |
| 54% | CACAO | 5 | With 3-Down, its seeds are the source of chocolate |
| 54% | ERIE | 4 | Great Lake with 3 vowels in its name |
| 54% | EDAM | 4 | It pairs well with pinot noir |
| 52% | EDAM | 4 | Aged, it pairs well with pears |
| 51% | TALLAHASSEE | 11 | Major U.S. city with three pairs of double letters in its name |
| 50% | ETA | 3 | Letter between a pair that rhyme with it |
| 49% | TRAIL | 5 | With 3-Down, backpacker's snack |
| 49% | NEA | 3 | 3.2 million-member org. with a pi in its logo |
| 48% | WHALE | 5 | With 3-Down, world's largest fish |
| 48% | ANIL | 4 | It's to dye with |
| 48% | FACT | 4 | It's never 3-Down |
| 47% | ALAN | 4 | With 3 Down, ''M*A*S*H'' star |
| 47% | BIB | 3 | It's usually served with lobster |
| 47% | BONGO | 5 | It's not played with sticks |
| 47% | USUAL | 5 | It's nothing new, with "the" |
| 47% | TIME | 4 | It's often shown with hands |