| 100% | PEI | 3 | It's separated from N.B. by the Northumberland Strait |
| 71% | ASIA | 4 | It's separated from North America by the Bering Strait |
| 49% | WHEAT | 5 | It's separated from the chaff |
| 47% | CHIOS | 5 | Greek island separated from Turkey by a strait of the same name |
| 46% | IRELAND | 7 | It's separated from Iceland by a sea (and a "c"!) |
| 45% | VANCOUVER | 9 | Island separated from the Canadian mainland by the Strait of Georgia and Queen Charlotte Sound |
| 45% | SUMATRA | 7 | It's across the strait from Singapore |
| 44% | ALASKA | 6 | State separated from Asia by the Bering Strait |
| 44% | SRILANKA | 8 | Island separated from India by the Palk Strait |
| 43% | LABRADOR | 8 | It's across the Strait of Belle Isle from Newfoundland |
| 42% | SIDE | 4 | It's often served on a separate plate from the main course |
| 41% | EXCLAVE | 7 | Part of a country that's separated from its mainland and surrounded by different country |
| 40% | ONT | 3 | It's across the St. Lawrence from N.Y. |
| 39% | CURB | 4 | It separates the street from the sidewalk |
| 38% | LAGOON | 6 | Body of water separated from the sea by a reef |
| 38% | BRAN | 4 | Husks of cereal grain separated from the flour by sifting |
| 38% | LAGOON | 6 | Body of water separated from the ocean by a reef |
| 38% | SAMOA | 5 | The Apolima Strait separates its two main islands |
| 38% | ALASKAPENINSULA | 15 | It separates the Bering Sea from the Pacific |
| 38% | STRAITOFMESSINA | 15 | It separates Sicily from the rest of Italy |
| 38% | NORTH | 5 | ___ Vancouver, Canadian suburbian city separated from Vancouver by the Burrard Inlet |
| 37% | AOC | 3 | N.Y.C. rep from whom the D.S.A.’s national committee withdrew its endorsement (July, 2024) |
| 37% | CHAFF | 5 | It's separated by winnowing |
| 37% | SAMOS | 5 | Island in the Aegean Sea separated from Turkey by the Mycale Strait |
| 37% | ERA | 3 | "It's the end of an ___" (line by Joey from "Friends") |
| 37% | ALDERNEY | 8 | Island separated from the Cap de la Hague, France, by the Race of — |
| 37% | EUBOEA | 6 | Greek island believed to have been separated from the mainland by an earthquake |
| 36% | TUNIS | 5 | World capital whose name can be formed by removing letters from the end of its country's name |
| 36% | THANET | 6 | Isle of —, area of Kent formerly separated from the mainland by the Wantsum Channel |
| 36% | ISLEOF | 6 | & 15A Area of NE Kent formerly separated from the mainland by the Wantsum Channel |