| 100% | ESTIMATED | 9 | It's the E in an aircraft's ETA |
| 57% | ENERGY | 6 | It's the E in "e equals mc2" |
| 57% | INTERFACE | 9 | It's the I in an HDMI cable |
| 57% | TOKEN | 5 | It's the T in an online NFT |
| 56% | EMERGENCY | 9 | It's the E in the United Nations' UNEF |
| 56% | ELECTRIC | 8 | It's the E in American manufacturing company GE |
| 56% | ENERGY | 6 | It's the e in Einstein's equation e = mc2 |
| 54% | LSD | 3 | It's the "acid" in an acid trip: Abbr. |
| 53% | MINUET | 6 | It's done in the form of an S or a Z |
| 51% | PHI | 3 | When repeated, it's the name of an island group in Thailand |
| 50% | LISP | 4 | "Whose cruel idea was it for the word '___' to have an S in it?" (Steven Wright joke) |
| 50% | ESTIMATED | 9 | The E in ETA |
| 50% | ONEPIN | 6 | It's located in the middle of an alley |
| 49% | RETURNADDRESS | 13 | It's often found in the upper-left corner of an envelope |
| 49% | SYSTEM | 6 | It's the S in Apple's iOS |
| 48% | SYSTEM | 6 | It's the S in Apple's iOS technology |
| 48% | SYNDROME | 8 | It's the S in AIDS, IBS and PMS |
| 47% | STAMP | 5 | It's put in the top-right corner of an envelope |
| 47% | CORNCOBPIPE | 11 | It's made from an ear and put in the mouth |
| 47% | STAMP | 5 | It's put in the top right corner of an envelope |
| 47% | SCREEN | 6 | It's the S in cinema and television's SAG Awards |
| 46% | OPEC | 4 | It imposed an embargo on the U.S. in 1973 |
| 46% | OHIO | 4 | It's high in the middle and round at both ends, in an old joke |
| 46% | EXTRA | 5 | Newsboy's shout in an old movie (or the actor who shouts it) |
| 46% | GRAND | 5 | The ___ Canyon, Arizona's rocky attraction with an "enormous" synonym in its name |
| 46% | ONEBASE | 7 | What a walk in the ballpark will get you / (next line) It's spelled out in an Aretha Franklin hit |
| 45% | DOE | 3 | Rae, the deer in an Olive Brinker webcomic, e.g. |
| 45% | HIJACKING | 9 | The taking over of an aircraft in flight |
| 45% | STAT | 4 | "It's urgent" in the E.R. |
| 45% | EGAL | 4 | It's the same in Paris |