| 100% | OED | 3 | It added "essential worker" in March of 2021: Abbr. |
| 45% | OED | 3 | Ref. that added gig economy and essential worker in 2021 |
| 42% | DST | 3 | It starts in March: Abbr. |
| 40% | OED | 3 | “Awesomesauce” was added to it in 2020: Abbr. |
| 39% | TKO | 3 | It may result in abrupt ending of a boxing match: Abbr. |
| 39% | SUNY | 4 | Schools in Albany and Oneonta are part of it: Abbr. |
| 38% | AEG | 3 | German producer of electrical equipment with its headquarters in Frankfurt: Abbr. |
| 38% | SHOWMESTATE | 11 | Nickname of Missouri, which celebrates its bicentennial in 2021 (3 wds.) |
| 38% | CMA | 3 | Group that voted Luke Combs its 2021 Entertainer of the Year: Abbr. |
| 37% | IDES | 4 | Beware of it in March, technically the fifteenth |
| 37% | ECOL | 4 | Branch of biology which studies any organism in relation to its environment: Abbr. |
| 37% | MTM | 3 | ___ enterprises, sitcom producer of the 70s with a cat in its logo: Abbr. |
| 37% | APA | 3 | Organization that removed homosexuality from its list of mental disorders in 1973: Abbr. |
| 37% | MTM | 3 | ___ enterprises, sitcom producer of the '70s with a cat in its logo: Abbr. |
| 37% | RNA | 3 | Polymeric molecule essential in expression of genes: Abbr. |
| 37% | DST | 3 | It begins in March (Abbr.) |
| 36% | SOUSAPHONE | 10 | It dots the "i" in the Ohio State marching band's spelling of "Ohio" |
| 36% | PETA | 4 | Animal-focused group that named Billie Eilish its 2021 Person of the Year: Abbr. |
| 36% | ASL | 3 | It's sometimes seen in the corner of a TV screen: Abbr. |
| 36% | ITAL | 4 | It adds stress: Abbr. |
| 35% | OAN | 3 | American cable news channel with an Eagle in its logo operating out of San Diego: Abbr. |
| 35% | FOREMAN | 7 | Worker in charge of others |
| 35% | DST | 3 | Cause of a lost hour in March: Abbr. |
| 34% | RNS | 3 | Some essential workers: Abbr. |
| 34% | NHL | 3 | Sports group that added the Seattle Kraken in 2021: Abbr. |
| 34% | BLEEDS | 6 | "If It ___," collection of four novellas by Stephen King that was nominated for a Locus Award in 2021 |
| 34% | TODDRUNDGREN | 12 | "Hello It's Me" singer inducted into the Rock and Roll Hall of Fame in 2021: 2 wds. |
| 34% | ISR | 3 | U.S. ally whose capital has the letters U-S-A in the middle of its name: Abbr. |
| 34% | SDAK | 4 | Only U.S. state in which the name of the state and its capital share no letters: Abbr. |
| 34% | ERS | 3 | Workplaces for some essential workers, in brief |