| 100% | EDO | 3 | It was replaced by "Tokyo" |
| 84% | ABA | 3 | It was replaced by the NBA: Abbr. |
| 84% | NAFTA | 5 | It was replaced by USMCA in 2020 |
| 78% | ROYALWE | 7 | I may be replaced by it |
| 74% | CURSEWORD | 9 | It might be replaced by symbols |
| 73% | NAFTA | 5 | Commerce pact to be replaced by USMCA when it's ratified |
| 73% | CURSEWORD | 9 | It may be replaced by a dash |
| 64% | VARIABLE | 8 | In the answers to 17-, 34- and 57-Across, it was replaced in turn by 1, 2, 3, 4, 5 ... |
| 64% | GIVEWAYTO | 9 | Be replaced by: 3 wds. |
| 61% | PETE | 4 | Best who was replaced by Ringo |
| 61% | FRANC | 5 | Coin being replaced by the euro |
| 61% | LAWNS | 5 | They might be replaced by xeriscaping |
| 61% | MARSBARS | 8 | They were replaced by Snickers Almonds |
| 60% | EDO | 3 | It is now Tokyo |
| 60% | TELEX | 5 | Communication method that was replaced by fax |
| 60% | KRONE | 5 | Monetary unit being replaced by the euro |
| 60% | CPA | 3 | Pro that may be replaced by TurboTax |
| 60% | RENEWABLE | 9 | Capable of being replaced by new growth |
| 60% | PAPERCHECK | 10 | *Payment method being replaced by mobile banking |
| 60% | NAFTA | 5 | Agreement to be replaced by the USMCA |
| 60% | IMDEAD | 6 | “LMAO” equivalent that might be replaced by “💀” |
| 59% | AGENA | 5 | It was boosted by Titan |
| 59% | AGENA | 5 | It was boosted by Atlas |
| 59% | KNEE | 4 | It was taken by Kaepernick |
| 59% | LATIN | 5 | It was spoken by Romans |
| 59% | LENO | 4 | Late-night host who was replaced by Fallon |
| 59% | IRON | 4 | Monopoly token that was replaced by a cat |
| 59% | GUILDERS | 8 | Dutch currency before they were replaced by euros |
| 59% | PER | 3 | Word that may be replaced by a slash |
| 58% | CAT | 3 | It was killed by curiosity, apparently |